Chp 1-3 Book Flashcards
an imaging tech created from sonor technology
ultrasound
microscopic examination of a frozen tissue specimen is an application of ….
histology
what is a cell
the basic structural and functional units of all living orgnisms
the changes an organism undergoes through time
development
in a negetive feedback mechanism, the response of the effector
is to make the deviation from the set point smaller
what is one of the structures contained in the mediastinum
esophagus
the plane that cuts the body lengthwise and seperates the body into anterior and posterior portions
frontal
What is anatomy?
scientific discipline that investigates the bodys structure (shape/size)
What is physiology?
scientific investigation of the processes or function of living things
What are the four topics of anatomy?
regional- area by area
systemic- system by system
surface- external form and relation to deeper structures as Xray in anatomic imaging
cytology- the study of cell
histology- tissues
what are the three topics of physiology?
cell- processes in cells
neurophysiology- nervous system
cardiovascular- heart and blood vessels
anatomical imaging
radiography, ultrasound, mri to create picture of internal structures. allows amazing accuracy without trauma.
What are two subjects that encompass both anatomy and physiology?
pathology
exercise physiology
pathology
structural and functional changes caused by disease
exercise physiology
changes in structure and function caused by disease
what are the six levels of organization?
chemical- atoms/molecules
cell- functional unit of life
tissue- similar cells
organ- several tissues
organ system- several organs
organism- a living thing
What are the organ systems of the body?
integumentary, skeletal, muscular, nervous, endocrine, cardiovascular, lymphatic, respiratory, digestive, urinary, reproductive
What are the 6 characteristics of human organism?
organization- specific relationships and functions
metabolism- chemical reactions of body
responsiveness- ability to sense changes
growth- increase in size and number of cells
development- changes in organism over time
reproduction- new cells or new organism
What are the two types of development?
differentiation- change from general to specific
morphogenesis- change in shape of tissues, organs.
What is homeostasis?
the existence and maintenance of a relatively constant environment within the body
set point
the ideal normal value of a variable
what are the two types of feedback system?
negative and positive
what are the three components of a feedback system?
receptor - monitors the value of some variable
control center - establishes set point
effector - change the value of the variable in response
What is negative feedback?
any deviation from the set point is made smaller
what is positive feedback?
when a deviation occurs, the response is to make the deviation greater
what is one example that positive feedback is good?
childbirth
What is the anatomical position?
body erect, face forward, feet together, palms face forward.
What is supine?
laying face up
What is prone?
lying face down
superior vs. inferior
toward the head and away from the head.
medial vs. lateral
toward the midline or away from
proximal vs distal
closer to point of attachment or farther away
superficial vs. deep
relative to the surface of the body
anterior vs posterior
forward and toward the back
What are the abdominal subdivisions
epigastic, hypochodriac, umbilical, lumbar, hypogastric, iliac
What are the four body planes
median
frontal or coronal
transverse
oblique
What are the three serous membranes?
pericardium- heart
pleura- lungs
peritoneum- abdominopelvic
What are the six kinds of imaging techniques?
radiography- xray
ultrasound - US
computed tomography- CT
digital subtraction angiography- DSA
magnetic resonance imaging- MRI
positron emission tomography- PET
radiography
shadowy negative of internal body structures
ultrasound
computer analyzed sound waves bounced off a structure
CT scan
computer analyzed composite of radiograph; shows slices of body
DSA
comparision of radiographs with and without dye
MRI
uses magnetism and radio waves to look for varying alignments of protons in soft tissues.
PET
uses radioactively labeled glucose- calculates metabolic activity of cells.
What is an element?
simplest type of matter with unique chemical properties
What is an atom?
smallest particle of an element that has chemical characteristic of that element
neutron
no charge
proton
positive charge
electron
negatively charged particle
Chemical bonds
when an electron is transferred or shared.
ionic bond
when an electron is lost or shared
covalent bond
when electron is shared
What is a molecule?
two or more atoms combine
What is a compound?
two or more atoms combine (different atoms)
What is a catalyst?
a substance that increases a chemical reaction without being depleted.
What is an enzyme?
a protein catalyst.
What is inorganic chemistry?
deals with substances that do not contain carbon.
What is a solution?
any mixture of liquid, gas, or solid.
What is an acid?
a proton donor - Ph less than 7
What is a base?
a proton acceptor
What is organic chemistry?
study of carbon containing substances
What are the four major groups needed for living things
carbohydrates
lipids
proteins
nucleic acid
What is the basic structure of the cell?
plasma membrane
cytoplasm
nucleus
plasma membrane
cell membrane, forms outer bondary of the cell
cytoplasm
between the two - contains organelles, jelly substance
nucleus
directs cell activity
organelles
specilized structures that perform specific functions
What are the 4 functions of the cell
- cell metabolism and energy use
- synthesis of molecules
- communication
- reproduction and inheritence
How is DNA exchanged?
gametes cells exchange DNA during sexual intercourse
What does the plasma membrane do?
separate inter-cellular from extracellular.
What is membrane potential?
a charge across the membrane from intracellular and extracellular ion concentrations.
What are the two types of glycocalyx
glycolipids - carbs +lipids
glycoproteins - carbs +proteins
What makes up the membrane lipids
phospholipids and cholesterol
What are the two types of membrane proteins
integral or intrinsic- extend deeply into membrane
peripheral or extrinsic- attached to integral proteins at either the inner or outer surfaces of lipid bilayer
What does membrane functioning depend on?
3D shape and chemical characteristics
Do membrane proteins matter?
marker molecules
attachment proteins
transport proteins
enzymes
receptor proteins
What are marker proteins
glycoproteins and glycolipids
cells identify each other.
What are the two types of attachment proteins
cadherins - cells to cells
integrins - integral proteins that attach to extracellular molecule.
What are the three types of transport proteins?
channel
carrier
ATP powered
What are the two types of Channel proteins?
nongated ion channels -always open. plasma membrane permeable to a few ions when the plasma membrane is at rest.
gated - opened/closed by stimuli
What are the two types of gated ion channels
ligand - opens - a small molecule binds to proteins or glycoproteins
voltage - opens - a change in charge across plasma membrane
What are the several forms of carrier proteins
uniporter- moves one particle
symporters- moves two particles in same direction at same time
antiporters - move two particles opposite directions at same time.
ATP powered transport depends on
concentration of substrate and ATP
What do the enzymes in the plasma membrane act to
catalyze reactions at outer/inner surface of plasma membrane.
What are the two types of receptor proteins
Receptors- linked to Channel Proteins
Receptors- linked to G protein complexes
Kinds of passive membrane transport
diffusion
osmosis
facilitated diffusion
kinds of active membrane transport
active transport
secondary active transport
vesicular transport
What is diffusion
movement of solutes in solution. higher concentration to lower concentration
What are the three parts of diffusion
concentration - difference between two points
viscosity - how easily liquid flows
temperature - affects the movement of particles.
What is osmosis?
diffusion of water across a selectively permeable membrane. water from area of low concentration to area of high concentration.
What is osmotic pressure?
force required to prevent water from moving across a membrane by osmosis
isomotic
solutions with same concentration of solute particles.
What is hyperosmotic
solution with a greater concentration of solute.
What is hyposmotic
solution with a lesser concentration of solute.
isotonic solution
cell neither shrinks nor swells
hypertonic solution
cell shrinks -crenation
hypotonic solution
cell swells -lysis
What does facilitated diffusion do?
move large, water soluble molecules or electrically charged molecules across membrane.
What does active transport depend on?
concentration of substrate and ATP
What is secondary active transport?
ions or molecules move in same or different direction.
What is endocytosis
internalization of substances - formation of vesicle.
What are the types of endocytosis
phagocytosis
pinocytosis
receptor mediated endocytosis
What is exocytosis
secretions expelled from the cell
What are the four parts of the cytoplasm
cytosol
cytoskeleton
cytoplasmic inclusions
organelles
What are the three parts of the cytoskeleton
microtubules
intermediate filaments
actin filaments
What is the cytosol
fluid portion of the cytoplasm
What does the cytoskeleton do
supports the cell
What are microtubules
hollow, internal scaffold, transport in cell, cell division.
What are cytoplasmic inclusions
aggregates of chemicals
What are organelles
small specilized structures- with specific structure/function.
What is part of chromosome structure
DNA + proteins
What are the two types of ribosomes
free and attached.
What are the two types of endoplasmic reticulum
rough - attached - proteins produced and modified
smooth - not attached - lipids and carbohydrates
What is the purpose of the gogli apparatus
modifications, packaging, distribution of proteisn and lipids
What are the two membranes on the mitochondria
cristae
matrix
Where are microtubules made
centrosome
Whats cilia
appendages projecting from cell surfaces
Whats microvilli
extension of plasma membrane
What is a gene
functional unit of heredity
What are the two types of genes
structural- serve as template fro mRNA
regulatory- control which structural genes transcribes in given tissue
What is transcription
DNA used to form mRNA
What is translation
synthesis of a protein at the ribosomes using mRNA< tRNA and rRNA.
What four things happen in transcription
DNA strands are seperated
RNA polymerase binds at promoter region
RNA polymerase helps form mRNA chain using DNA
transcription ends at terminator sequence
What does mRNA do?
directs polypeptide production.
Where does translation occur
ribosomes in cytoplasm
What is an interphase
phase between cell divisions
What are the four phases of cell division
prophase
metaphase
anaphase
telophase
What happens in metaphase
chromosomes are aligned at nuclear equator
What happens in anaphase
spindle fibers seperate the chromatids
What happens in telophase
chromosomes decondense
What happens in prophase
nuclear envelope disintegrates
What is cyrokinesis
cytoplasmic division.
What are the two steps in replication of DNA
DNA strands seperate
old strands become templates for new strands to form.
Human anatomy and physiology is the basis for what?
understanding disease
What does the word anatomy mean?
to dissect or cut apart and separate the parts of the body for study.
What does developmental anatomy study
the structural changes that occur between conception and adulthood.
What is embryology
a subspecialty of developmental anatomy, considers changes from conception to the end of the eight week of development.
What is cytology
examines the structural features of cells
What is histology
examines tissues, which are composed of cells and the materials surronding them
What is gross anatomy
the study of structures that can be examined without the aid of microscope, can be approached either systemically or regionally.
What is a system
a group of structures that have one or more common functions, such as cardiovascular, nervous, respiratory, skeletal, or muscular systems.
What is surface anatomy
involves looking at the exterior of the body to visualize structures deeper inside the body.
What are anatomical anomalies?
physical characteristics that differ from the normal pattern.
What is celWhat are the two types of systemic physiologyl physiology
examines the processes occuring in cells such as energy production from food
What is systemic physiology
considers the functions of organ systems.
What are the two types of systemic physiology
cardiovascular
neurophysiology
What is pathology
is the medical science dealing with all aspects of disease, with an emphasis on the cause and development of abnormal conditions, as well as the structural and functional changes resulting in disease.
What is exercise physiology?
focuses on the changes in function and structure caused by exercise.
What are the six levels of organization
chemical, cell, tissue, organ, organ system, organism
What does the chemical level involve
how atoms, interact and combine into molecules.
What does molecules structure determine
its function
What are cells
are the basic structural and functional units of all living organisms.
What do organelles do?
carry out particular functions, such as digestion and movement, for the cell.
What is human health dependent upon?
the health of our microbiota, the good bacteria.
What is a tissue
is composed of a group of similar cells and the materials surrounding them.
What are the 4 types of tissues?
epithelial, connective, muscle, nervous.
What is an organ
is composed of two or more tissue types that perform one or more common functions.
What determines the function of a tissue?
the characteristics of the cells and surrounding materials.
What are the major goals when studying human physiology
to understand and predict the body responses to stimuli and to understand how the body maintains conditions within a narrow range of values in a constantly changing environment.
What is an organ system
A group of organs working together to perform a particular function
What are the 11 major organ system?
integumentary, skeletal, muscular, nervous, endocrine, cardiovascular, lymphatic, respiratory, digestive, urinary, reproductive.
What is an organism
is any living thing considered as a whole- whether composed of one cell, or trillions of cells
organization
refers to the specific interrelationships among the parts of an organism and how those parts interact to perform specific functions.
What is metabolism
is the ability to use energy and to perform vital functions.
The shape of a molecule determines its what
function
What is metabolism necessary for?
vital functions like responsiveness, growth, development, and reproduction.
What is responsiveness
an organism ability to sense changes in its external or internal environment and adjust to those changes.
What does growth refer to?
an increase in the size or number of cells, which produces an overall enlargement of all or parts of an organism.
What is development
the changes an organism undergoes through time, beginning with fertilization and ending at death.
differentiation
involves changes in a cells structure and function from an immature, generalized state to a mature, specialized state.
What is morphogenesis
is the change in shape of tissues, organs, and the entire organism.
What is reproduction
the formation of new cells or new organism.
What are the six characteristics of life
organization
metabolism
responsiveness
growth
development
reproduction
homeostasis
the existence and maintenance of a relatively constant environment within the body
What must a body do to acheive homeostasis
the body must activly regulate conditions that are constantly changing
What must happen for a cell to function normally?
the volume, temp, and chemical content of their environment must be maintained within a narrow range.
What is one of the most well known examples of homeostasis
body temperature
What is negative feedback
when any deviation from the set point is made smaller or is resisted.
What are the three components of a negative feedback system
receptor, control center, effector.
What is a receptor
monitors the value of a variable such as body temp by detecting stimuli
What is the control center
determines the set point for the variable and receives input from the receptor about the variable
What is an effector
can adjust the value of the variable when directed y the control center, usually back towards the set point.
What is Orthostatic hypotension
is a significant drop in blood pressure upon standing
What are metabolic pathways
are chemical reactions driven by biological protein catalysts called enzymes.
What is positive feedback
occurs when a response to the original stimulus results in the deviation from the set point becoming even greater.
What is an examples of a normal positive feedback
birth, blood clots
What are the two basic principles about homeostatic mechanisms
many disease states result from the failure of negative feedback to maintain homeostasis.
some positive feedback mechanism can be detrimental instead of helpful.
What is one example of a detrimental positive feedback mechanism
inadequate delivery of blood to cardiac muscle
What is the anatomical position
refers to a person standing erect with the face directed forward, the upper limbs hanging to the sides, and the palms of the hands facing forward.
What does the sufix itis mean
inflammation
what does anterior mean
in front of
What does posterior mean
behind
What does ventral mean
towards the belly
What does dorsal mean
toward the back
proximal
closer to point of attachment
What does distal mean
farther from point of attachment
What does lateral mean
away from midline
What does medial mean
toward the midline
What is the term superior exchanged with
cephalic
What is the term inferior exchanged with
caudal
What does the central region of the body consist of
the head, neck, and trunk
What regions can the trunk be divided into
thorax, abdomen, pelvis.
What are the nine regions of the abdomen
epigastric, hypochindriac, umbilical, lumbar, hypogastric, iliac.
Saggital plane
seperates the body into right and left halves.
Median plane
saggital plane that passes through the midline of the body, dividing into equal halves.
Transverse plane
runs parrallel to the ground, dividing the body into superior and inferior portions.
Frontal plane
divides the body tino front and back halves.
What are the two types of internal cavities
dorsal and ventral body cavities.
What does the dorsal cavity enclose?
the organs of the nervous system, brain, and spinal cord.
What are the two subdivisions of the dorsal body cavity
cranial and vertebral
What are the two divisions of the ventral body cavity
thoracic cavity, abdominopelvic.
What can the thoraicic cavity be divided into
pleural cavaties, medial mediastinum
What is the parietal serous membrane
the layer that lines the walls of the cavity
What is the visceral serous membrane
the layer covering the internal organs.
What is the pleural cavity
contains the lungs
What is the peritoneal cavity
houses liver, digestive organs, and reproductive.
What are mesenteries
regions of double folded visceral peritoneum.
What do mesenteries provide
a pathway fro nerves and blood vessels to reach the digestive organs.
What does retroperitoneal mean
behind the peritoneum.
What is pericarditis
an inflammation of the serous pericardium.
What is cardiac tamponade
is a potentially fatal condition in which a large volume of fluid or blood accumulates in the pericardial cavity and compresses the heart from the outside.
What are some causes of cardiac tamponade
rupture of the heart wall, rupture of blood vessels in pericardium, damage to pericardium due to radiation therapy, and trauma.
What is pleurisy
inflammation of the pleura
What is peritonitis
inflammation of the peritoneum
What does chemicals compose?
the structures of the body and the interactions of chemicals with one another are responsible for the body’s functions.
What is chemistry
the scientific discipline concerned with the atomic composition of substances and the reactions they undergo.
What is matter
anything that occupies space
What is mass
the amount of matter in an object.
What is weight
the gravitational force acting on an object of a given force.
What is the international unit for mass
kilogram
What is an element
the simpliest type of matter, having unique chemical properties.
What is an atom
the smallest particle of an element that has chemical characteristics of that element. .
What is an element composed of
atoms of only one kind.
What does the characteristics of matter result from
the structure, organization, behavior of atoms
What is an electron cloud
the region where electrons are most likely to be found
How is each element uniquely defined
by the number of protons in the atoms of that element.