A+P 11-14 Flashcards
what are the functions of the nervous ssytem
sensory input integration homeostasis mental activity control
what are the components of the nervous system
brain, spinal cord, nerves, sensory receptors
What are the subdivisions of the nervous system
central- brian and spinal
peripheral- sensory receptors and nerves
what are sensory recepetors
ending sof hte neurons or specialized cells. detect pain, touch, pressure.
What is a nerve
bundle of axons + sheaths, connects CNS to sensory recpetors, muscles, and glands.
What are the two kinds of nerves
cranial and spinal
What is ganglion
neuron cell bodies outside CNS
What is plexus
axons outside CNS
how many pairs of cranial and spinal nerves are in the nervous system
12, 31
what are the divisions of the PNS
sensory- transmits action potentials from receptors to CNS
motor- transmit action potentials from CNS to effectors
what are the two divisions of the motor system
somatic
autonomic
what are the divisions of the autonomic system
sympathetic
parasympathetic
enteric
which systme is a single neuron
motor division of PNS
what is synapse
axons forming the junction of a neuron with another cell
neuromuscular junction
synapse between the neuron and a skeletal muscle fiber.
what is the two neuron system
autonomic nervous system
why is the autonomic system a two neuron system
CNS to ganglion and Ganglion to effector
What is a sympathetic system
most active during physcial activity
What is the parasynthetic system
regulates resting functions. such as digesting food
What is enteric
plexues in walls of digestive tract.
what is the organization of the nervous system
receptor- sensory NC- CNS- Motor NS- effector
What is purpose of the neurons
receive stimuli and transmit action potentials.
what is neuroglia
support and protect neurons
What is cell body
primary site of protein synthesis
What are dendrites
short, often highly branched.
What are dendritic spines
little protuberances where axons synapse with dendrite.
what is inital segment
beginning of axon
what is trigger zone
site where action potentials are generated.
what is axoplasm
like cytoplasm of the axon
what is axolemma
axons plasma membrane
what are the two forms of axonic transport
away from body
into the cell
how are neurons classified structurally
multipolar- many dendrites with a single axon
bipolar- one dendrite one axon
pseudounipolar- most sendory neurons. single process
how are neurons classified functionally
sensory
motor
interneurons
what are the 4 types of neuroglia of CNS
astrocytes
ependymal
microglia
oligodendrocytes
what are astrocytes
processes form feet- cover sruface of neurons and blood vessels
What do astrocytes promotes
formation of blood brain barrier
what determines what substances can pass from the blood into the nervous tissue of the brain and spinal cord
astrocytes
what do astrocytes allow exchange of
nutrients and waste products between neurons and blood
What do astrocytes prevent fluctuations in blood composition from affecting the brain
What do astrocytes regulate extracellular brain fluid composition.
where are ependymal cells
line brain ventricles and spinal cord central canal
what are choroid plexuses
secrete cerebrospinal fluid.
what are oligodendrocytes
form myelin sheaths if they surrond an axon many times.
what can single oligodendrocytes form
myelin sheaths around portions of several axons.
what are schwann cels
wrap many times around a portion of only one axon- forms myelin sheath
what does myelin do
protects and insulates axons from one another, speedis transmission of APs.
what are unmyelinated axons
not wrapped around the axon.
what is white matter
axons form bundles
what is grey matter
neuron cell bodies and their dendrites are grouped together with very little myelin
what is gray matter on the surface of the brain called
cortex
what are deeper clusters in the brain called
nuclei
what is cluster of neuron cell bodies
ganglion
what are satellite cells
surrond neuron cell bodies in sonsory ganglia.
what do satellite cells provide
support and nutrients to the nueron cell bodies.
what are action potentials
cells produce electrical signals.
what do electrical properties result from
ion concentration difference across plasma membrane
permeability of membrane to ions.
what is the ion concetration of cell due to
the Na/K pump
membrane permeability
what are 4 kinds of gated ion channels
ligand
voltage
touch
temperature
true
true or false
at rest, more K+ and Cl- are moving than Na+
where is K+ in higher concetration
inside the cell
how do ligand gated channels work
ligand binding to receptor protein.
how do voltage gated channels work
when cell is stimulated charge changes- voltage gate ion channels open or close
how do touch receptors work
mechanical stimulation of skin opens gates
how do temperature receptors work
temperature changes in skin opens gates
what is the resting membrane potential
number of charged ions inside=outside.
what is potential difference
electrical charge difference across the plasma membrane is -70 to -90 mV
what happens with the greater charge difference
greater potential difference
what happens if extracellular concetration of K+ increases
depolarization
what happens if extracellular ion concentration decreases
hyperpolarization.
what happens if you chane the concetration of Na+ inside or outside the cell
very little effect
what happens as Na+ diffuses in
depolarization
what are voltage gated Na+ channels sensitive to
Ca2+ concentration.
what is hypocalcemia
uncontrolled concentration of skeletal muscles
increases membrane permeability to Na+
what is a graded potential
a small change in the RMP confined toa small area of the plasma membrane
what do graded potentials result from
ligand binding changes in charge mechanical stimulation teperature changes spontaneous chanfe permeability
whats ummate mean
add onto each other
when is a AP created
local potential reaches threshold
what are action potentials
permeability changes when a local potential causes depolarization of membrane.
what is all on none principle
if stimuli greater than threshold
what are the two phases of action potentials
depolarization
repolarization
what are the two parts of the refractory period.
absolute
relative
what is the absolute
beginning of action potential o near end of repolarization.
what is relative
a stronger than threshold stimulus can initiate another action potential.
what is action potential frequency
number of action potentials produced per unit of time to a stimulis.
what is supramaximal stimulis
stronger than maximal.
what is action potential propagation
AP at one site causes Ap at next location by stimulating voltage gated Na+ channels in adjacent regions of the membrane.
what is synapse
junction between two cells where they communicate with each other.
what are two types of synaptic cells
presynaptic cells
postsynaptic cells
what are connexons
protein tubes
where are electrical synapses found
cardiac and smooth muscle cells.
what does electrical synapses allow for
coordinated contractile activity among groups of cells.
what are synaptic vesicles
Ap causes Ca2+ to eneter cell.
what is postsynaptic membrane
ACh binds to ligand gated Na+ channels.
neurotransmitter substnaces are stored in vesicles located in specialized portions of the
axon
neuromodulators
substance released from neurons
neuromodulators
can influence the likelyhood that an AP in the presynaptic terminal will result in an AP in the postsynaptic cell.
excitory effects on the CNS
increase levels of NE in synaptic cleft.
increase release of norepinephrine from synaptic vesicles in presynaptic neuron.
decrease appetite, increase alertness
enhances ability to concentrate
what is used to treat depression
prozana and zoloft
axoaxonic synapses
axon of one neuron synapses with the presynaptic terminal of another.
presynaptic inhibition
reduction in amount of neurotransmitter released from presynaptic terminal
what is morphine
bind to endophin and enkephalin receptors in presynaptic neurons
what is presynaptic facilitation
increases neurotransmitter released from presynaptic terminal.
what does caffeine stimulate
release of glutamate in the brain.
blocks adenosine receptors and keeps adenosine from doing its job
promotes alertness
convergent pathways
many converge- synapse with smaller number of neurons
divergent pathways
smal number of presynaptic neurons synapse with large number of postsynaptic neurons
what are the segments of the spinal cord
cervical
thoracic
lumbar
sacral
what are the two enlargemnts of the spinal cord
cervical
lumbosacral
what is the conus medullaris
tapered inferior end
What is the cauda equina
orgin of spinal nerves
What is the filum terminale
anchors spinal cord to coccyx
what are meninges
connective tissue membranes
What are the layers of the meninges
dura matter
arachnoid matter
pia matter
what are denticulate ligaments
attach spinal cord to dura matter.
what are the sections between the spinal cord
epidural
subdural
subarachnoid
what is found in the epidural
blood, arealor CT, adipose, spinal nerve roots
what is in the subdural
serous fluid
What is in the subarachnoid
CSF, blood vessels, arachnoid
what is the anterior median fissure
deep cleft partially dividing left and right halves of spinal cord
what is a tract
a collection of axon inside the CNS
what is a nerve
a collection of axon outside the CNS
what is dorsal root ganglion
collections of cell bodies of pseudo unipolar sensory neurons
cell bodies for spinal sensory neurons are located in the
dorsal root ganglia
the spinal cord extends from the
medulla oblongata to the level of the 2nd lumbar vertebra
what is a reflex
an automatic response to a stimulis produced by a reflex arch
what is the basic functional unit of the nervous system
reflex arch