chapter 4 book Flashcards

1
Q

what are tissues

A

collection of specialized cells and the extracellular substances surrounding them.

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2
Q

how are body tissues classified into groups

A

structure of cells, composition of non-cellular substances, function of cells.

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3
Q

what are the four primary tissues

A

epithelial, connective, muscle, nervous.

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4
Q

how are epithelial and connective tissues classified

A

structure, cell shape, relationship of cell to another, composition of extracellular matrix.

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5
Q

how is muscle and nervous tissue classified

A

structure and functioning characteristics and location.

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6
Q

what is histology

A

microscopic study of tissues

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7
Q

what is biopsy

A

process of removing tissue samples from patients surgically or with a needle for diagnostic purposes.

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8
Q

what is an autopsy

A

examination of organs to determine the cause of death or to study the changes caused by disease.

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9
Q

what are the two layers of the embryonic stem cells

A

epiblast and hypoblast

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10
Q

what are the three embryonic germ layers

A

endoderm, mesoderm, ectoderm

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11
Q

what is the endoderm

A

inner layer, forms lining of digestive tract and derivaties.

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12
Q

what is the mesoderm

A

middle layer, forms tissies such as muscle, bone, and blood vessels

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13
Q

What is the ectoderm

A

outer layer, forms the skin

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14
Q

what is the neuroectoderm

A

portion of ectoderm that becomes nervous system.

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15
Q

what is neural crest cells

A

groups of cells that break away from neuroectoderm during development, give rise to parts of periphal nerves, skin pigment, the medulla o adrenal gland and many tissues of face.

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16
Q

what is epithelial tissue

A

covers and protects surfaces, both outside and inside body

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17
Q

What are some common characteristics of epithelial tissue

A
composed of cells
covers body surfaces
tissue surfaces
cell and matrix connections
nonvascular-diffusing across basement membrane
regeneration
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18
Q

what body surfaces does epithelial tissues cover

A

exterior, lining digestive and respitory tracts, heart and blood vessels, body cavities.

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19
Q

what tissue surfaces does epithelial tissue cover

A

apicol surface, lateral, basal

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20
Q

what is the apicol surface

A

cells are exposed and not attached to other cells

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21
Q

what is the lateral surface

A

cells attached to other epithelial cells

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22
Q

what is the basal surface

A

base of tissue, attached to basement membrane

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23
Q

what is the basement membrane

A

specialized type of extracellular material secreted by epithelial and connective tissue cells.

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24
Q

what is basement membranes important role

A

supporting and guiding cell migration during tissue repair.

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25
Q

what are major functions of epithelial tissues

A
protecting underlying structures
acting as barrier
permitting passage of substnaces
secreting substances
absorbing substances
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26
Q

how do epithelial tissues act as barriers

A

reduce water loss and prevent toxic molecules and microorganisms

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27
Q

what are the 4 types of epithelial tissues

A

simple epithelium
stratified epithelium
pseudo-stratified
transitional

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28
Q

what is simple epithelium

A

single layer cells, extending basement to free surface

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29
Q

what is stratified epithelium

A

more layer cells, basal layer attach to basement membrane

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30
Q

what is pseudostratified

A

special type of simple, one layer cell attached to basement membrane

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31
Q

what is transitional

A

special type stratified, cell changes from cubical and columnar to squamous when stretched.

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32
Q

what are the three types of epithelium

A

squamous, cubidoil, columnar.

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33
Q

what are two types of stratified squamous epithelium

A

nonkeratinized- consists of living cells in both deepest and superficial layers
keratinized- living cells in deepest layer, dead containing keratin protein in superficial.

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34
Q

Where is keratinized found

A

skin, gums, hard palate of mouth.

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35
Q

where is nonkeratinized found

A

mouth, esophagus, rectum, vagina.

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36
Q

what is transitional epithelium

A

lines urinary bladder, ureters, kidney and urethra. surface cells cuboid or columnar when not stretched, and squamous when stretched.

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37
Q

what is purpose of simple epithelium

A

covers internal organs, facilitates diffusion of gases on lungs, filters blood in kidneys, cellular products in glands, absorbs nutrients in intestines.

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38
Q

what is function of stratified epithelium

A

protection

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39
Q

where is stratified squamous found

A

in areas of body where abrasion can occur, such as skin, mouth, pharynx, esophagus, anus, vagina.

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40
Q

what is the shape of cells that filter

A

flat and thin

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41
Q

what is the shape of cells that secrete

A

cubiodal or columnar.

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42
Q

what are goblet cells

A

specialized columnar epithelial cells. responsible for synthesizing and secreting mucus.

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43
Q

what are free surfaces

A

not in contact with other cells

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44
Q

what are the types of free surfaces

A

smooth, microvilli, folded, cilia.

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45
Q

what is microvilli

A

nonmotile, contain microfilaments, extensions of clll that increase surface area, occur in cells that absorb or secrete, such as serous membrane and lining of small intestine.

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46
Q

what is a ground substance

A

gel mile mixture of nonfiberous molecules

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47
Q

what are the two major components of ground substance

A

hyaluronic and proteoglycans

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48
Q

what is hyaluronic acid

A

long, unbranched polysaccharide chain composed of repeating disaccharide units.

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49
Q

what is a proteoglycan

A

large molecule consist of protien core attached to many long polysaccharides called glycosaminoglycans.

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50
Q

what are adhesive molecules

A

ground substance hold proteoglycans aggregates together.

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51
Q

what is chondronectin

A

ground substance of cartilege

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52
Q

what is fibronectin

A

ground substance of fiberous connective tissue

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53
Q

what are two major connective tissue

A

embryonic connective

mucous connective

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54
Q

what is embryonic connective tissue

A

composed of fibrofblasts surronded by semifluid extracellular matrix containing delicate reticular fibers.

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55
Q

what is mucous connective tissue

A

umbilical cord, sim to that of mesenchyme, rich source of stem cells.

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56
Q

what are the three types of adult connective tissue

A

connective tissue, fluid connective, supporting connective.

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57
Q

what is loose connective tissue

A

consist of relatively few protein fibers that form lacy netweork with numerous spaces filled with ground substance and fluid.

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58
Q

what are 3 subdivisions of connective tissue

A

areoler, adipose, reticular.

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59
Q

what is areoler tissue

A

loose packing material of most organs and tissues. attaches skin to underlying tissues. contains collegen, reticular, and elastic fibers.

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60
Q

what is adipose tissue

A

connective tissue with special properties- composed of large cells and small amount of extracellular matrix.

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61
Q

what does adipose tissue function as

A

insulator and site of energy storage.

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62
Q

what are two types of adipose tissue

A

yellow

brown

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63
Q

what is yellow adipose tissue

A

appears white at birth, turns yellow with age becuas accumulation of pigments, carotene, plant pigment

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64
Q

what is brown adipose tissue

A

found in armpits, neck, kidneys.

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65
Q

what is reticular tissue

A

form framework of lymphatic tissue. spleen. lymphocytes, bone marrow.

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66
Q

what is dense connective tissue

A

large number protein fibers, form thick bundles and fill extracellular space.

67
Q

what does dense regular collagenous connective tissue form

A

form tendons, ligaments.

68
Q

what is the general structure of tendons.

A

collagen fibers of ligaments often less compact.
some fibers not parallel
ligaments more flattened than tendons and form sheets and bands of tissues.

69
Q

what is dense regular elastic connective tissue

A

parallel bundles of collagen fibers and abundant elastic fibers.

70
Q

what is dense irregular connective tissue

A

contains protein fibers aranged as mashwork of randomly oriented fibers.

71
Q

what is irregular collagenous connective tissue

A

forms dermis, surronds kidney and spleen.

72
Q

what is dense irregular elastic connective tissue

A

elastic arteries, layers of tissue contain abundant elastic fibers.

73
Q

what is cartilege

A

composed of cartilege cells with extensive and rigid matrix.

74
Q

what is perichondrium

A

dense tissue surronding the surface of cartilege.

75
Q

lacunae

A

spaces in whcih cartilege cells are located.

76
Q

what are the three types of cartilege

A

hyaline
fibro
elastic

77
Q

what is lyaline cartilege?

A

large amounts collogen fibers and proteoglycans. glassy translucient matrix when viewed trhough microscope
found where strong support and some flexiability. involved in growth that increases lenght of bones.

78
Q

what is fibro

A

thicker bundles collogan fibers, slightly compresable and tough

79
Q

where is fibro found

A

knee, jaw, vertebra

80
Q

what is purpose of fibro

A

absorb shock and prevent bone to bone abrasion

81
Q

what is elastic

A

found in areas that rigid but elastic properties.

82
Q

what is bone

A

hard connective tissue that consists of living cells and mineralized matrix.

83
Q

what is osteocytes

A

bone cells, located within holes in matrix.

84
Q

what are two types of bone

A

compact- no space between thin layers or lamellae

spongy

85
Q

what is blood

A

liquid matrix allos to flow rapidly through body, carry nutrients, oxygen, waste products.

86
Q

what is hemopoetic tissue

A

forms blood cells, found in bone marrow

87
Q

what are two types of bone marrow

A

red marrow- surronded by reticular fibers

yellow- yellow adipose tisse and not produce blood cells.

88
Q

what is stereocillia

A

specialized microvilli found primarily in sensory structures such as inner ear

89
Q

what is cilia

A

motile and contain microtubules, allow to move across free surface of cell.

90
Q

what are cell connections

A

mechanically bind cells together, help form permeable layer, provide mechanism fro intercellular communication.

91
Q

what are desmosomes

A

adhesive glycoproteins that bind cells together and intercellular proteins attached to intermediate filaments that extend tinto cytoplasm of cells.

92
Q

what are hemidesmosomes

A

similar to one half of e3, attach epithelial cells to the basement membrane.

93
Q

tight junctions

A

hold cells together and form permeable layer. formed by proteins in plasma membrane of adjacent cells that join one another to make a very tight seal.

94
Q

what does tight junction form

A

ring that surrounds cell and binds cells together to prevent passage of material between cells.

95
Q

where are tight junctions found

A

areas where layers of simple epithelium form permeable layer.

96
Q

what is adhesive belt

A

glycoproteins is found below tight junction, acts as weak glue that holds cells together.

97
Q

what is gap junction

A

small, specialized contact regio between cells containing protein channels that aid intercellular communication by allowing ions and small molecules to pass from one cell to another.

98
Q

what is intercalculated disks

A

contain gap junctions and desomes that help hold adjacent cells in close contact.

99
Q

what are glands

A

composed of epithelium, with supporting network of connective tissue. develop from infolding or outfolding of epithelium in embryo

100
Q

what exocrine glands

A

glands with ducts

101
Q

whats hormones

A

cellular products of endocrine products

102
Q

whats multicellular glands

A

exocrine glands composed of many cells

103
Q

whats goblet cells

A

unicellular glands that secrete mucus

104
Q

what are the types of multicellular glands

A

simple, compound, tubular, acinar, alveolar, tubuloacinar, tubuloalveolar

105
Q

what are the types of exocrine gland secretion

A

merocrine- involves release of secretory products by exocytosis used by water producing sweat glands
apocrine- involves release of secretory products as pinched off fragments of gland cells
holocrine- shedding of entire cells product accum in cytoplasm, cell ruptures and dies, entire cell is secreted.

106
Q

what are major functions of connective tissue

A
enclosing and seperating tissue
connective tissue to another.
supporting and moving parts of body
storing compounds
cushioning
transporting
protecting
107
Q

what is a blast

creates matrix

A

creates matrix

108
Q

maintains matrix

A

what is a cytes

109
Q

what is a clasts

A

breakdown for remodeling

110
Q

what is adipocytes

A

adipose cells, cotain large amount of lipid
thin layer cytoplasm
abundants in loose connective tissue

111
Q

what is mast cells

A

released in response to injury, trauma and infection.

112
Q

what is white blood cells

A

move from blood vessel to connective tissue. increases with injury

113
Q

what is lymphocytes

A

common in connective tissue under epithelial lining of digestive tract.

114
Q

what is macrophages

A

large, phagocytic cells, derived from monocytes.

115
Q

what are 2 types of macropages

A

fixed, wandering

116
Q

what are platelets

A

fragments of hemopoietic cells containing enzymes and special proteins that function in clotting process.

117
Q

what are undifferentiated mesenchymal cells

A

adult stem cell, potential to form multiple cell types. fibroblasts or smooth muscle cells, response to injury

118
Q

what are three types of protien fibers

A

collagen, reticular, elastic.

119
Q

what are collagen fibers

A

strong and flexible, like microscopicropes but not very elastic.

120
Q

what is type 1 collagen

A

suited for tendons, ligaments, bone, skin, some flexiability

121
Q

what is type 2 collagen

A

cartilege

122
Q

what is type 3 collagen

A

reticular fibers

123
Q

whats reticular fibers

A

very short, thin fibers that branch to form netwrok.

124
Q

what are elastic fibers

A

protein has ability to return to origianl shape after stretched or compressed.

125
Q

what are three types muscle tissues

A

skeletal, cardiac, smooth muscle.

126
Q

what is skeletal muscle.

A

located attached to bones. very long. cylindrical cells, moves body

127
Q

what is cardiac muscles

A

located in heart. cylindrical cells that branch, function provides major force for moving blood through blood vessels.

128
Q

what is smooth muscles

A

located in walls of hollow organs, blood vessels, eyes, glands, skin. spindle shaped. moves food through digestive tract, empties urinary bladder, regulates blood vessel diameter.

129
Q

what is nervous tissue

A

brain, spinal, cord, nerves, characterized by ability to conduct electrical signals, consists or neurons and glia.

130
Q

what is neurons

A

conduciting cells of tissue, transport electrical signals throughout body.

131
Q

what are the neuron components

A

cell body
dendrites
axon

132
Q

what is cell body

A

contains nucleus and site of general cell functions

133
Q

what is dendrites

A

receive action protentials, branches at ends

134
Q

what is axon

A

conducts actin potentials away from cell body, constant diameter along entire lenght.

135
Q

what are multipolar neurons

A

multiple dendrites and single axon

136
Q

what is bipolar neurons

A

single dendrite and axon

137
Q

what is pseudo unipolar neurons

A

single, short process extends from cell body and divides into two branches.

138
Q

what is gilia

A

support cells of brain, spinal cord, peripheral nerves.

139
Q

what is mucous membrane

A

lines cavities and canals that open to outside of body.

140
Q

what is components of mucous membrane

A

epithelial cells, basement membrane, connective tissue, lamina.

141
Q

what is components of serous membrane

A

layer of squamous epithelium called mesothelium, basement membrane, delicate layer of connective tissue, do not contain glands.

142
Q

what is purpose of serous membrane

A

protect internal organs from friction, help hold in place, selectively permeable membrane.

143
Q

what is synovial membrane

A

line freely movable joints, made of connective tissue.

144
Q

what is synovial fluid

A

rich in hyaluronic acod.

145
Q

what is inflammation

A

response that occurs when tissues develop

146
Q

what is imflammatory response

A

defense mechanism that mobilizes bodys immune cells to isolate and destroy microorganisms and remove damaged cells.

147
Q

what are chemical mediators

A

stimulate pain receptors and increase permeability of blood vessels.

148
Q

what does edema do

A

increase pressure in tissue, stimulate neurons and cause pain.

149
Q

what is tissue repair

A

sub of viable cells for dead cells by regeneration or replacement

150
Q

what is regeneration

A

new cells are same type that have been destroyed.

151
Q

what is replacement

A

new type cell develops, which produces scar and causes loss of tissue function.

152
Q

what is labile cells

A

always divide, undifferiated cells in bone marrow, study turnover of new cells replacing old cells.

153
Q

where is labile cells found

A

skin, mucous membrane, lymphatic tissue.

154
Q

what is stable cells

A

connective tissues, liver, endocrone glands, capable of regeneration in response to injury.

155
Q

what is permanent cells

A

neurons, skeletal, cardiac muscle, not able to replicate response to injury

156
Q

what is primary union

A

if edges of wound close together. wound fills with blood and clot forms.

157
Q

what is secondary union

A

edges not close together, tissue loss extensive.

158
Q

what is fibrin

A

threadlike protein which binds edges of wound together.

159
Q

what is granulation tissue

A

delicate, granular appearing connective tissue that consist of fibroblasts, collagen, capillaries.

160
Q

what is carcinoma

A

cancer derived from epithelial tissue

161
Q

what is adencarcinomas

A

types of carsinomas derived from glandular epithelium

162
Q

what is sarcoma

A

rare type of cancer derived from mesodermal tissue.

163
Q

what does atherosclerosis results from

A

plaque forms in walls of blood vessels, which contain collagen fibers, lipids, calcium deposits.