Cholinergic Drugs Flashcards
two mechanisms of action for parasympathomimetics
direct
indirect
what does direct parasympathomimetic action do
mimics acetycholine
what does indirect parasympathomimetic action do
inhibit the breakdown of acetylcholine via cholinesterase
five clinical uses of cholinergic drugs
Stimulate GI motility
Control vomiting
Treat urinary retention
Reduce IOP in glaucoma
Act as an antidote for neuromuscular blockers
five adverse effects of cholinergic drugs
Bradycardia
Hypotension
Heart block
SLUDGE
Increased bronchial secretions
which direct cholinergic drug is rarely used because it is broken down too rapidly
Acetylcholine
which direct cholinergic drug is used to increase bladder tone
Bethanechol
what direct cholinergic drug is used to decrease intraocular pressure in glaucoma
Pilocarpine
which direct cholinergic drug is used to control vomiting and promote GI tract emptying
Metoclopramide
which indirect cholinergic drug is related to insecticides
organophosphate
neurotransmitter of the parasympathetic nervous system
acetylcholine
