Cholesterol Flashcards
What is cholesterol?
Lipid that can be distinguished by its characteristic four ring structure
What types of cells have cholesterol?
eukaryotes
What does cholesterol do in the cell membrane?
modulates the membrane fluidity
by making the membrane:
Less fluid at warmer temperatures
More fluid at colder temperatures
Cholesterol does this by binding adjacent
phospholipids together.
When temperatures rise, the cholesterol
prevents rips in the membrane from
occurring by holding the phospholipids
together.
When temperatures lower, the
cholesterol
prevents the membrane from freezing solid, by acting as a spacer between the phospholipid molecules.
What types of cells have cholesterol?
found in high quantities in animal cells
Why is cholesterol Cholesterol found in high
quantities in animal cells?
because animal cells don’t have a cell wall to maintain their structure, but still need to be flexible (fluid).
Describe the structural placement of cholesterol within the cell membrane
Cholesterol fits between phospholipids in the cell membrane with its hydroxyl (-OH) group, by the heads
and the hydrophobic rings by the tails
Cholesterol of cold blooded animals vs warm
Cold blooded animals (who can’t regulate body temperatures) tend to have more cholesterol than warm-blooded.
Membranes must be fluid enough…
- for the cell to move
- for the required substances to move across them
Membranes if too fluid…
won’t be able to regulate effectively what substances move in and out (think of holes or rips occurring in the
membrane).