chlamydiae

Question 1

chlamydiae characteristics

Answer 1

small, gram negative
no murein in cell walls
obligate intracellular pathogens
depend on host for ATP

Question 2

chlamydial infections are leading cause of ____ and the most common agents of ____

Answer 2

preventable blindness; sexually transmitted bacterial infections

Question 3

___ infections are genital tract infections caused by chlamydial bacteria

Answer 3

C. trachomatis

Question 4

during birth, infants can contract C. trachomatic infection, leading to ____ and _____

Answer 4

conjunctivitis; pneumonia

Question 5

Inflammation of the conjuctiva, can cause blindness, scarring of cornea

Answer 5

trachoma (c. trachomatis strain)

Question 6

STD

Systemic, invasive infection apparent in the lymph nodes that drain the genital tract

Answer 6

lymphogranuloma venerum

Question 7

Perhaps the most prevalent chlamydial pathogen in the human population;Usually asymptomatic or acute respiratory response, but chronic respiratory infections have been associated with asthma, CF, lung cancer

Answer 7

chlamydophila pneumoniae

Question 8

chlamydophila pneumoniae can be directly observed in 40-100% of patients with _____

Answer 8

atherosclerotic heart lesions

Question 9

____ forms are targets of antimicrobials for chlamydia

Answer 9

metabolic active RB

Question 10

antimicrobials must penetrate 4 membrane layers:

Answer 10

1. host cell plasma membrane
2. inclusion membrane
3. chlamydial outer membrane
4. chlamydial cytoplasmic membrane