Chapters 17 and 18 Flashcards
What is a hormone?
A chemical secreted and responded to inside the body
What a pheromone?
A chemical released externally that communicates with others/environment
What is an autocrine signal?
A hormone that acts on the same cell type that secretes it (happens within the cell or tissue)
What is an example of an autocrine signal?
prostaglandin acting on vascular smooth muscle
What is a paracrine signal?
Affects a different cell type than the type that secreted it. Happens locally, not transported in the blood
What is an example of a paracrine signal?
release of somatostatin by the pancreas to inhibit insulin
Amplitude modulated signals
Endocrine regulated
More chemical = larger response
Slower response
Potentially longer duration
Frequency modulated signal
Nerve impulses
Multiple signals build action potential
Fast response
Short duration
Pattern one of hormone regulation and secretion
something other than a hormone acts on an endocrine gland, usually via negative feedback
pattern two of hormone regulation and secretion
neural control of an endocrine gland, such as sympathetic/parasympathetic responses
Give two examples of pattern two of hormone regulation
secretion of epinephrine by adrenal glands (sympathetic)
secretion of gastrin by the stomach for digestion (parasympathetic)
Pattern Three of hormone regulation and secretion
control of secretion of one endocrine gland by a hormone or neurohormone of another endocrine gland
another name for pattern three is..
a hormone cascade
Which hormones often function in pattern three?
reproductive and thyroid hormones
Give some examples of hormone control by negative feedback
calcium regulation by calcitonin and PTH or blood sugar regulation by insulin and glucagon
give some an example of hormone control by positive feedback
oxytocin causing more and more labor contractions
What is the difference between endocrine glands and exocrine glands as pertains to ducts?
Endocrine glands do not have ducts, exocrine glands do have ducts because they secrete into cavities or onto body surfaces
What is the exocrine function of the pancreas?
secreting digestive juices into the stomach
what is the endocrine function of the pancreas?
secreting insulin, glucagon, and somatostatin
What portion of the pancreas has endocrine functions?
pancreatic islets (Isles of Langerhans)
What type of cells in the pancreatic islets secrete hormones?
alpha, beta, and delta cells
explain the specificity of hormones
Hormones are specific because target organs have specific receptors for only those hormones. If no receptor, hormone will not bind and no change will take place
at what frequency are hormones secreted?
Based on bodily demands, usually not continuous
How do hormone responses compare to nervous responses?
Hormone responses usually take longer to start, but then last longer than nervous system responses
What carries hormones to remote target organs?
the circulatory system
membrane bound hormone receptors
bound to plasma membrane, bind to water soluble and larger weight, non-steroid hormones
intracellular hormone receptors
receptors inside the cell that bind to lipid soluble hormones
antagonistic hormone pairs
hormones working in opposite conditions to one another to maintain homeostasis
examples of antagonistic hormone pairs
calcitonin and PTH
insulin and glucagon
synergistic hormone responses
hormones that work together to produce a response