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Oral Pathology > Chapter 9 > Flashcards

Chapter 9 Flashcards

1
Q
A

Transient Lingual Papilliits - Localized

1+ enlarged papilla - red/yellow

Painful

Anterior doral tongue

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2
Q
A

Transient Lingual Papillitis - Generalized

Large percent of fungiform papilla involved

Tip and lateral dorsal tongue

Painful and sensitive

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3
Q
A

Recurrent Apthous Ulcerations - Minor

Most common form

Occurs in childhood

3-10 mm lesions

1-5 lesions

7-14 days healing time

No Scarring

Fewest recurrences

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4
Q
A

Recurrent Aphthous Ulcerations - Major

“Sutton’s Disease”

Occurs in adolescents

1-3 cm lesions

1-10 lesions

Healing time 2-6 weeks

Scarring is possilbe

More recurrences than minor, less than herpetiform

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5
Q
A

Recurrent Aphthous Ulcerations - Herpetic Form

Occurs in adults

1-3 mm lesions

Up to 100 lesions

Healing time 2-4 weeks

Scarring

Most recurrences

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6
Q

Treatment of Recurrent Aphthous Ulcerations

A

Minor cases = no treatment

Major cases, multiple recurrences = clobetasol proprionate (.05% steroid for pain)

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7
Q

Transient Lingual Papillitis

A
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8
Q

Diffuse papulokeratotic variant

A

Large number of affected papilla –> transient papillitis

All papilla affected - all over the otngue

Apearance: elevated, white or yellow

Asymptomatic

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9
Q

Treatment for Transient Lingual Papillitis

A

Resolve w/o therapy

Topical steroids reduce pain

Magic mouthwash - malox, benadryl, lidocaine viscous

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10
Q

Recurrent Aphthous Ulcerations

A

AKA Recurrent aphthous stomatitiis

Very Common - 30%

Occur exclusively on MOVABLE MUCOSA

Clinical variations: minor, major, herpetiform

Younger patients

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11
Q

Behcet’s syndrome

A

Chronic, recurrent immune disease

Includes:

Oral aphthous-like ulcerations

Ocular inflammation

Genital ulcers

Skin lesions

Arthralgia

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12
Q

Sarcoidosis

A

Multisystem granulomatous disorder

Afican Americans >>>> Caucasions

90% Abnormal x-ray

25% skin lesions on head and neck and lower legs

Syndromes:

Lofgren’s syndrome

Heerfordt’s syndrome

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13
Q

Syndromes of Sarcoidosis

A
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14
Q

Lofgren’s Syndrome

A

Erythema nodosum

Bilateral hilar lymphadeopathy

Arthralgia

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15
Q

Heerfordt’s Syndrome

A

Parotid Enlargment

Inflammation of the eye

Facial paralysis

Fever

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16
Q

Organs involved in Sarcoidosis

A

Lungs

Lymph nodes

Skin

Eyes

Salivary glands

17
Q

Lupus pernio

A

Chronic, purple, indurated lesion on head and neck

18
Q

Erythema nodosum

A

Scattered, nonspecific, tender, red nodules on lower legs

19
Q

Sarcoidosis - Histology

A

Non caseating granulomatous inflammation

Schaumann bodies (degenerated lysosomes)

Asteroid Bodies (entrapped collagen fragments)

Hamazaki-Weseberg bodies (large lysosomes)

20
Q

Sarcoidosis - Diagnosis

A

Elevated serum angiotensin-converting enzyme levels

Chest x-ray

Kveim test - no longer used

21
Q

Orofacial Granulomatosis

A

Variable presentation

Lips are most commonly involved

If only lips are invovled = cheilitis granulomatosa

Syndrome - Melkersson-Rosenthal syndrome

Histology - granulomatous inflammation

22
Q

Melkersson-Rosenthal Syndrome

A

Cheilitis granulomatosa

Facial paralysis

Fissured tongue

23
Q

clobetasol proprionate

A

Used for treatment of major or recurring apthough ulcers

24
Q

Skin lesion of Sarcoidosis

A

Lupus Pernio

Erythema Nodosum

25
Q

Wegener’s Granulomatosis

A

Necrotizing granulomatous lesions of Respiratory tract, glomerulonephritis, systemic vascluitis

If untreated –rapid renal involement –> DEATH

Oral lesions

26
Q
A

STRAWBERRY GINGIVITIS

Oral lesions of Wegner’s Granulomatosis

Early manifestation

Appearance: Florid, erythematous, granular hyperplasia

27
Q

Diagnosis of Wegner’s Granulomatosis

A

Indirect inmmunofluorescence detects presence of antineutrophil cytoplasm antibodies

Perinuclear (p-ANCA)

Cytoplasmic (c-ANCA) – most useful

28
Q

Treatment of Wegner’s Granulamostosis

A

STERIODS – first line tx (75% survival)

Untreated – 10% two year survival (necrotixing glomerulonephritis)

29
Q

Contact Stomatitis from Cinnamon

A

Reactions associated with pronlonged or frequent contact (candy, chewing gum, toothpaste)

Gingiva can appear large and red –> plasma cell gingivitis

Superficial slough of tissue (similar to sodiun laryl-sulfate containing toothpaste)

Localized lesions –> ulcerated, white, red

Signs –> disappear within 1 week discontinued use

30
Q

Angioedema

A

Quincke’s Disease

DIffuse edematous swelling of the soft tissue

No pain

Itching and erythema

Quick onset

common cause –> mast cell degranulation leads to histamine release

** IgE mediated hypersensitivity **

Diffuse involvement of the head and neck –> caused by angiotensin-converting enzyme (ACE) inhibitors

31
Q

Treatment for allergic angioedema

A

Oral antihistamine therapy

IM epinephrine and IV corticosteriods for SEVERE cases

32
Q

What are some angiotensin-converting enzyme inhibitors?

A

-prils (lisinopril)

Medication used for HTN or chronic heart failure

Swelling associated with these drugs do not respond well to antihistamines

33
Q

Treatmen tof ACE inhbitor associated angioedema

A

Avoid all ACE inhbitor medications

monitor until swelling subsides

C1-INH concentrate

34
Q

Anigioedema vs Orofacial granulomatosis

A

Angioedema -> quick onset

Orofacial (chelitis) granulomatosis –> slow onset

35
Q

Recurrent apthough ulcers vs HSV

A

Recurrent apthous ulcers –> MOVABLE mucosa

HSV –> MOVABLE and ATTACHED mucosa

36
Q

Where do Major RAU generally occur?

A

Labial mucosa

Soft pallate

Tonsillar faucets

Oral Pathology (17 decks)

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