Chapter 80: Dietary Supplements, Natural & Complementary Medicine Flashcards

1
Q

DSHEA requires the manufacturer to ensure that their products are ___ before they are marketed

A

safe

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2
Q

Drugs must be proven to be ___ & ___ before they can be sold

A

safe & effective

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3
Q

Adverse events from supplements can be reported to

A

The FDA’s Safety Reporting Portal

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4
Q

Supplements cannot claim

A

to treat, cure or mitigate (lessen) a condition

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5
Q

What are the 4 areas of concern with supplements

A

Drug interactions, increased bleeding risk, or cause hepatotoxicity or cardiotoxicity

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6
Q

Folic acid 600 mcg DFE = ___ mcg of folic acid daily

A

400 (the RDA for women in child-bering years)

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7
Q

St. John’s Wort should be avoided with which classes of drugs

A

MAOi, SSRIs and SNRIs (it is serotonergic)

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8
Q

St. John’s Wort causes _____ & requires counseling on ___ and avoidance

A

Photosensitivity

Sun protection

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9
Q

Which supplements can increase bleeding risk

A
  • Remember the 5 G’s: ginger, gingko, garlic, ginseng & glucosamine
  • Fish oils (at higher doses)
  • Vitamin E
  • Dong quai
  • Willow Bark (a salicylate)
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10
Q

Which supplements can be hepatotoxic

A
  • black cohosh (used for menopausal symptoms)

- Kava (used for stress/anxiety)

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11
Q

Which supplements can be cardiototoxic

A
  • Ephedra (removed from market) - bitter orange (synephrine) replaced ephedra in many products (these drugs are stimulants)
  • Yohimbe (used to increase libido & for ED)
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12
Q

Which supplements can be used for anxiety

A
  • Valerian
  • Passionflower
  • Kava
  • St. John’s Wort
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13
Q

Which supplement can be used for ADHD

A

omega-3 fatty acids

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14
Q

Which supplement can be used for Cold sores

A

L-lysine

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15
Q

Which supplements can be used for colds and flu

A
  • Echinacea
  • Zinc
  • Vitamin C
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16
Q

Which supplements can be used for dementia/memory

A
  • Ginkgo

- Vitamin E

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17
Q

Which supplements can be used for depression

A
  • St. John’s Wort
  • SAMe
  • Valerian
  • 5-HTP
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18
Q

Which supplements can be used for diabetes

A
  • Alpha lipoic acid
  • Chromium
  • Cassia cinnamon
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19
Q

Which supplements can be used for dyslipidemia

A
  • Red yeast rice

- Omega-3 FA

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20
Q

Which supplements can be used for dyspepsia

A
  • Calcium

- Magnesium

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21
Q

Which supplements can be used for energy/weight loss

A
  • Bitter orange
  • Caffeine
  • Guarana, green tea powder
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22
Q

Which supplements can be used for erectile dysfunction

A
  • Ginseng
  • L-arginine
  • Yohimbe
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23
Q

Which supplements can be used for HF/heart health

A
  • Coenzyme Q10
  • Hawthorn
  • Omega-3 FA
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24
Q

Which supplements can be used for HTN

A
  • Omega-3 FA
  • L-arginine
  • Coenzyme Q10
  • Garlic
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25
Which supplements can be used for GI health
- Fibers - chamomile - Probiotics
26
Which supplements can be used for inflammation
- Omega-3 FA - Flax seeds/oil - Turmeric
27
Which supplements can be used for insomnia/sleep
- Melatonin for sleep (taken QHS)/jetlag (0.5-2 mg taken pre-flight & higher doses like 5 mg taken post-flight) - Valerian - Chamomile
28
Which supplement can be used for liver disease
Milk thistle
29
Which supplements can be used for menopause
- Black cohosh - Dong quai - Evening primrose oil - Soy, red clover
30
Which supplements can be used for migraine, ppx
- Feverfew - Butterbur - Magnesium - Riboflavin
31
Which supplements can be used for motion sickness
- Ginger | - Peppermint
32
Which supplements can be used for osteoarthritis
- Glucosamine - Chondroitin - SAMe - Turmeric
33
Which supplements can be used for osteoporosis
- Calcium - Vitamin D - Soy
34
Which supplements can be used for prostate health
- Saw palmetto | - Lycopene
35
Which supplement can be used for skin conditions like acne, dandruff, and fungal infections
Tea tree oil
36
Which supplement can be used for UTI
Cranberry
37
Bitter orange safety issue
Stimulant (synephrine component)
38
Black cohosh safety issue
May be hepatotoxic
39
5-HTP safety issue
serotonergic
40
Caffeine safety issue
Increases BP and HR
41
Dong quai safety issue
Bleeding risk
42
Hawthorn safety issue
Positive inotrope; avoid concurrent use with digoxin (additive effect)
43
Kava safety issue
Avoid d/t hepatotoxicity
44
Omega-3 FA safety issue
Increases bleeding risk with high doses
45
Probiotics safety issue
Safety concern with use of live bacteria in immune-compromised states
46
Red yeast rice contains a natural form of
lovastatin
47
SAMe safety issue
serotonergic
48
Valerian safety issue
Sedation
49
Vitamin E alternative name
alpha-tocopherol
50
Vitamin E safety issue
bleeding risk, CVD risk
51
Thiamine deficiency can cause
Wernicke's encephalopathy
52
Symptoms of Wernicke's encephalopathy
mental confusion, ataxia, tremor and vision changes
53
As the symptoms of Wernicke's encephalopathy fade, which syndrome tends to develop
Korsakoff syndrome
54
Which vitamin are most alcoholics deficient in
B1 (thiamine)
55
Anticonvulsants can contribute to which vitamin deficiency
Calcium
56
Exclusively breast fed infants need how many IU of vitamin D daily
400 IU
57
All women of childbearing age should obtain ___ mcg/daily of folic acid
400
58
During pregnancy, folate requirements increase to ___ mcg/day
600
59
How long before pregnancy should folate be started
at least 1 month before
60
Prescription prenantal vitamins usually contain ____ mcg of folate
1000 mcg or 1 g
61
Too much vitamin E can cause
CVD risk
62
Breastfed babies need __ mg/kg/day of iron from 4-6 months old and until consuming iron-rich foods
1
63
When should Poly-Vi-Sol Vitamin drops be used
if both vitamin D and iron are needed
64
Amphotericin B depletes which vitamin(s)
Mg, K
65
Isoniazid depletes which vitamin(s)
B6
66
Loop diuretics deplete which vitamin(s)
K
67
Metformin depletes which vitamin(s)
B12
68
MTX depletes which vitamin(s)
Folate
69
Orlistat depletes which vitamin(s)
Beta-carotene, fat-soluble vitamins
70
PPIs deplete which vitamin(s)
Mg
71
Recommended supplement(s) for alcoholism
Vitamin B1
72
Recommended supplement(s) for microcytic anemia
Ferrous sulfate
73
Recommended supplement(s) for macrocytic anemia
B12 and/or folate
74
Recommended supplement(s) in pregnancy
Folate, Ca, Vitamin D, pyridoxine
75
Recommended supplement(s) for osteopenia/osteoporosis
Ca, Vit D
76
Recommended supplement(s) for CKD
Vitamin D