Chapter 8; Cardiovascular Drugs Flashcards

1
Q

Increasing the Force

A

Positive Inotropes

Cardiac glycosides

Adrenergic drugs

Benzimidazole-pyridazones

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2
Q

Increasing the Force: Cardiac glycosides

A

Digitalis drugs e.g. digoxin

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3
Q

Increasing the Force: Adrenergic Drugs

epinephrine

A

Non-selective for alpha 1, beta 1 and beta 2 receptors

Side effect: arrhythmias and hypertension

IV or IT (1:10 000 dilution)

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4
Q

Increasing the Force: Adrenergic Drugs

dopamine

A

Norepinephrine precursor

non-selective for aplha 1 and beta 1 receptors

IV

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5
Q

Increasing the Force: Adrenergic Drugs

dobtamine

A

Selective for beta 1 receptor

IV

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6
Q

Increasing the Force: Benzimidazole-pyridazones

pimobendin (VETmedin)

A

Approved drugs for dogs

increases ventricular contractility by sensitizing cariac muscle to calcium

Vasodilator - descreased preload and afterload

CHF - valvular insufficiency, dilated cardiomyopthy

Chewable tablets

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7
Q

Fixing the Rythm

A

Antiarrhythmic Drugs

Local Anaesthetics

Beta Blockers

Calcium Channel Blocker

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8
Q

Fixing the Rythm: Local Anaesthetics

lidocaine

A

Acture, emergency situations

Affects the action potential of cardiac cells, prevents Na++ infulx into myocardial cell during depolarization

IV

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9
Q

Fixing the Rythm: Beta Blocker

propranolol

A

selective antagonist of beta 1 and beta 2 receptors

IV or tablets

Side effects: bradycardia, bronchoconstriction, weakness

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10
Q

Fixing the Rythm: Calcium Channel Blocker

diltiazem

A

Block Ca++ channels od the myocardial call at SA and AV node

Tablets

Side effect: hyoptension

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11
Q

Correction Constriction

A

Vasodilators

Angiotensin-Converting Enzyme Inhibitors

Calsium Channel Blockers

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12
Q

Correction Constriction: Angiotensin-Converting Enzyme Inhibitors

enalapril (Encard) and benazepril (Fortekor)

A

Approved drug for dogs and cats

Prevent the conversion of angiotensin i to angiotensin ii

Tablets

Side effect: hyptension

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13
Q

Correction Constriction: Calcium Channel Blockers

amlodipine

A

Inhibits the movement of calcium through channels across myocardial cell membranes and vascular smooth muscle

Peripheral ateries dilate

Tablets

Side effect: hypertension in cats

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14
Q

Losing Fluid

A

Diuretics

Loop diuretics - furosemide

Potassium sparing diurtics - spironolactone

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