Chapter 11 Gastrointestinal Drugs

Question 1

Diarrhea Stopping Drugs: Adsorbents

activaited charcoal

Answer 1

Toxin ingestion

Question 2

Stool Loosing: Osmotics

Answer 2

For consipation

lactulose - liquid

polyethylene glycol; PEG 3350 - powder

Question 3

Vomit Stopping: Antiemetics

metoclopramide

Answer 3

Dopamine antagonist at CRTZ

Used for:

• gastric motility disorders
• megaesophagus

Oral or parenteral

Question 4

Vomit Stopping: Antiemetics

ondasetron

Question 5

Vomit Stopping: Antiemetics

maropitant (Cerenia)

Answer 5

NK1 receptor antagonist at CRTZ

Dogs and cats

Used for:

• acute vomiting
• motion sickness
• pre-travel vomiting

SC or PO

Question 6

Vomit Producing

apomorphine

Answer 6

Stimulate dopamine at CTRZ

Used for:

• poisoning

SC, IM or topically into conjunctival sac

Question 7

Ulcer Stopping Drugs: Histamine 2 Receptor Antagonist

Answer 7

ranitinde (Zantac) - SC or PO

famotidine (Pepside) - SC or PO

Question 8

Ulcer Stopping Drugs: Mucosal Protectant Drugs

sucralfate

Answer 8

Forms an adherent covering over ulcers and protects from acid

PO

Question 9

Ulcer Stopping Drugs: Prostaglandin Analogs

misoprostol

Question 10

Ulcer Stopping Drugs: Proton Pump Inhibitors

omeprazole

Question 11

Foam Stopping

poloxalene (Bloat Guard)

Answer 11

Reduce surface tension of bubbles

Ruminants

Stomach tube

Question 12

Motility Enhancing: Prokinetic Agents

cisapride

Question 13

Appetite Stimulant

cyproheptadine

Answer 13

Serotonin antagonist

Used for:

• anorexic cats

Question 14

Appetite Stimulant

mirtazapine

Answer 14

Tetracyclic antidepressant antagonizes alpha 2 receptors

Increase in norepinephrine

Used for:

• anorexic cats

Question 15

Appetite Stimulant

diazepam

Answer 15

Used for:

• anorexic cats

Hepatic toxicity in cats