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Pharamology > Antiparasitics > Flashcards

Antiparasitics Flashcards

1
Q

Antinematodal Drugs: Benzimidazoles

fenbendazole (Panacur)

A

Inhibit parasite energy metabolsim

Small Animals

Horses

Food animals

Birds

Reptiles

Small animals used for:

  • nematodes
  • hookworms
  • whipworms
  • cestode (Taenia)
  • Giardia

Oral

V/D

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2
Q

Antinematodal Drugs: Benzimidazoles

albendazole (Valbazen)

A

Inhibit parasite energy metabolism

Cattle

Used for:

  • nematodes
  • flukes
  • cestodes

Oral

V/D

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3
Q

Antinematodal Drugs: Benzimidazoles

febantel

A
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4
Q

Antinematodal Drugs: Tetrahyropyrimidines

pyrantel (Strongid T)

A

Disrupt neuromuscular transmission - cholinergic agonists

Muscle paralysis

Dogs and cats used for:

  • roundworms
  • hookworms

Horses and pigs used for:

  • ascarids
  • strongyles
  • pinworms
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5
Q

Antinematodal Drugs: Piperzines

piperazine compounds

A

Disrupt neuromuscular transmission - anticholingeric drugs

Used for:

  • ascarids

Small and large animals

High therapeutic range

Sold OTC

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6
Q

Antinedmatodal Drugs: Macrocyclic Lactones

ivermectin (Ivomec)

A
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7
Q

Antinedmatodal Drugs: Depsipeptides

emodepside

A

Disrupt neuromuscular transmission

Used for:

  • ascarids
  • hookworm

Cats

Topical

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8
Q

Anticestodal Drugs

praziquantel (Droncit) or (Milbemax)

A

Damage cell membrane integrity

Used for:

  • cestodes
  • Taenia
  • Echinoccus
  • Dipylidium

Often combined with other antiparasitics

Dogs and cats

Cats

V/D

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9
Q

Anticestodal Drugs

epsiprantel (Cestex)

A

Damage cell membrane integrity

Used for:

  • cestodes
  • Taenia
  • Dipylidium

Often combined with other antiparasitics

Dogs and Cats

V/D

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10
Q

Antitrematodal Drugs

albendazole (Valbazen)

A

Used for:

  • trematodes
  • flukes

Large animals

Withdrawal times

Not used in lactating dairy cows

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11
Q

Antiprotozoal Drugs

fenbendazole (Panacur)

A

Used for:

  • Giardia

Treatment of choice

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12
Q

Antiprotozoals Drugs

S125

S250

A

Used for

  • Coccidia

Small animals

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13
Q

Antiprotozoal Drugs

amprolium

A

Inhibits engery metabolism

Used for:

  • Coccidia

Poultry and rabbits

Feed aditive

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14
Q

Antiprotozoal Drugs

ponazuril (Marquis)

A

Inhibits engery metabolism

Used for:

  • protozoal

Horses

Oral paste

Soft feces

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15
Q

Ectoparasitic Drugs: Avermectins

ivermectin

A

Used for:

  • demodex

Dogs

Large animals

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16
Q

Ectoparasitic Drugs: Avermectins

selmectin

A

Used for:

  • fleas
  • ear mites
  • sarcoptic mange

Dogs and cats

17
Q

Ectoparasitic Drugs: Oragnophosphates

A

Insecticides/pesticides

Inhibit cholinesterase

Tremors

Hyperexcitability

SLUDDE

18
Q

Ectoparasitic Drugs

imidaclprid (Advantage) or (K9 Advantage)

A

Disrupts neuromuscular transmission; cholinergic agonist

Used for:

  • fleas

Dog and cat

Topical; monthly

19
Q

Ectoparasitic Drugs

spinosad (Comfortis)

A

Disrupts nueromuscular transmission; cholinergic agonist

Used for:

  • fleas

Dogs

Oral; monthly

20
Q

Ectoparasitic Drugs

nitepyram (Capstar)

A

Disrupts neuromuscular transmission; cholinergic antagonist (nicotinic receptors)

Used for:

  • fleas

Kills within an hour or less

Oral; daily

21
Q

Ectoparasitic Drugs

lufenuron (Program) or (Sentinel)

A

Interferes with exoskeleton and desposition of chitin

Used for:

  • flea pevention
  • flea contorl

Dogs and Cats

Dogs

Oral; monthly

22
Q

Heartworm Prevenion Medication: Macrocyclic lactones

ivermectin (Heartgard Plus)

A

Disrupt neuromuscular transmission

Prevents larvae transmitted by mosquito vector from reaching adult stage

Oral; monthly

23
Q

Heartworm Prevenion Medication: Macrocyclic lactones

selamectin (Revolution)

A

Disrupt neuromuscular transmission

Prevents larvae transmitted by mosquito vector from reaching adult stage

Topical; monthly

24
Q

Heartworm Prevention Medication: Macrocyclic lactones

milbemycin (Interceptor) or (Sentinel)

A

Disrupt neuromuscular transmission

Prevents larvae transmitted by mosquito vector from reaching adult stage

Oral; monthly

25
Q

Heartworm Prevention Medication: Macrocyclic lactones

moxidectin (Advantage Multi)

A

Disrupt neuromuscular transmission

Prevents larvae transmitted by mosquito vector from reaching adult stage

Topical; monthly

26
Q

Adult Heartworm Treatment

melarsomine (Immiticide)

A

Deep IM injection

Dog is kept quiet

Close monitoring for pulmonary emboli

27
Q

Microfilaria Treatment

ivermectin

milbemycin

A

Eliminates circulating microfilaria

Given at higher doeses

Pharamology (11 decks)

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