Antiparasitics Flashcards
Antinematodal Drugs: Benzimidazoles
fenbendazole (Panacur)
Inhibit parasite energy metabolsim
Small Animals
Horses
Food animals
Birds
Reptiles
Small animals used for:
- nematodes
- hookworms
- whipworms
- cestode (Taenia)
- Giardia
Oral
V/D
Antinematodal Drugs: Benzimidazoles
albendazole (Valbazen)
Inhibit parasite energy metabolism
Cattle
Used for:
- nematodes
- flukes
- cestodes
Oral
V/D
Antinematodal Drugs: Benzimidazoles
febantel
Antinematodal Drugs: Tetrahyropyrimidines
pyrantel (Strongid T)
Disrupt neuromuscular transmission - cholinergic agonists
Muscle paralysis
Dogs and cats used for:
- roundworms
- hookworms
Horses and pigs used for:
- ascarids
- strongyles
- pinworms
Antinematodal Drugs: Piperzines
piperazine compounds
Disrupt neuromuscular transmission - anticholingeric drugs
Used for:
- ascarids
Small and large animals
High therapeutic range
Sold OTC
Antinedmatodal Drugs: Macrocyclic Lactones
ivermectin (Ivomec)
Antinedmatodal Drugs: Depsipeptides
emodepside
Disrupt neuromuscular transmission
Used for:
- ascarids
- hookworm
Cats
Topical
Anticestodal Drugs
praziquantel (Droncit) or (Milbemax)
Damage cell membrane integrity
Used for:
- cestodes
- Taenia
- Echinoccus
- Dipylidium
Often combined with other antiparasitics
Dogs and cats
Cats
V/D
Anticestodal Drugs
epsiprantel (Cestex)
Damage cell membrane integrity
Used for:
- cestodes
- Taenia
- Dipylidium
Often combined with other antiparasitics
Dogs and Cats
V/D
Antitrematodal Drugs
albendazole (Valbazen)
Used for:
- trematodes
- flukes
Large animals
Withdrawal times
Not used in lactating dairy cows
Antiprotozoal Drugs
fenbendazole (Panacur)
Used for:
- Giardia
Treatment of choice
Antiprotozoals Drugs
S125
S250
Used for
- Coccidia
Small animals
Antiprotozoal Drugs
amprolium
Inhibits engery metabolism
Used for:
- Coccidia
Poultry and rabbits
Feed aditive
Antiprotozoal Drugs
ponazuril (Marquis)
Inhibits engery metabolism
Used for:
- protozoal
Horses
Oral paste
Soft feces
Ectoparasitic Drugs: Avermectins
ivermectin
Used for:
- demodex
Dogs
Large animals
Ectoparasitic Drugs: Avermectins
selmectin
Used for:
- fleas
- ear mites
- sarcoptic mange
Dogs and cats
Ectoparasitic Drugs: Oragnophosphates
Insecticides/pesticides
Inhibit cholinesterase
Tremors
Hyperexcitability
SLUDDE
Ectoparasitic Drugs
imidaclprid (Advantage) or (K9 Advantage)
Disrupts neuromuscular transmission; cholinergic agonist
Used for:
- fleas
Dog and cat
Topical; monthly
Ectoparasitic Drugs
spinosad (Comfortis)
Disrupts nueromuscular transmission; cholinergic agonist
Used for:
- fleas
Dogs
Oral; monthly
Ectoparasitic Drugs
nitepyram (Capstar)
Disrupts neuromuscular transmission; cholinergic antagonist (nicotinic receptors)
Used for:
- fleas
Kills within an hour or less
Oral; daily
Ectoparasitic Drugs
lufenuron (Program) or (Sentinel)
Interferes with exoskeleton and desposition of chitin
Used for:
- flea pevention
- flea contorl
Dogs and Cats
Dogs
Oral; monthly
Heartworm Prevenion Medication: Macrocyclic lactones
ivermectin (Heartgard Plus)
Disrupt neuromuscular transmission
Prevents larvae transmitted by mosquito vector from reaching adult stage
Oral; monthly
Heartworm Prevenion Medication: Macrocyclic lactones
selamectin (Revolution)
Disrupt neuromuscular transmission
Prevents larvae transmitted by mosquito vector from reaching adult stage
Topical; monthly
Heartworm Prevention Medication: Macrocyclic lactones
milbemycin (Interceptor) or (Sentinel)
Disrupt neuromuscular transmission
Prevents larvae transmitted by mosquito vector from reaching adult stage
Oral; monthly
Heartworm Prevention Medication: Macrocyclic lactones
moxidectin (Advantage Multi)
Disrupt neuromuscular transmission
Prevents larvae transmitted by mosquito vector from reaching adult stage
Topical; monthly
Adult Heartworm Treatment
melarsomine (Immiticide)
Deep IM injection
Dog is kept quiet
Close monitoring for pulmonary emboli
Microfilaria Treatment
ivermectin
milbemycin
Eliminates circulating microfilaria
Given at higher doeses
