Chapter 16 Anti-Inflammatory Drugs and Pain Reducing Drugs

Question 1

Steriod Anti-Inflammatory Drugs: Glucocorticoids

prednisolone

prednisone

Answer 1

Intermediate acting

Used for:

• inflammary conditions
• allergic reactions
• systemic disease

Topical

Oral

Parenteral

Inhaled

PU/PD/PP, supressed healing, thin skin, GI ulcers muscle wasting, Crushing’s Disease

Question 2

Steriod Anti-Inflammatory Drugs: Glucocorticoids

dexamthasone

Answer 2

Long acting

Used for:

inflammary conditions
 allergic reactions
 systemic disease

Topical

Oral

Parenteral

Inhaled

PU/PD/PP, supressed healing, thin skin, GI ulcers muscle wasting, Crushing’s Disease

Question 3

Non-Steroidal Anti-Inflammatory Drugs: NSAID

phenylbutazone

Answer 3

Inhibit cyclooxygenase and platelet aggregation

Horses

Oral, parenteral

GI ulcers, bleeding, renal necrosis (hypotension, dehydration, pre-existing renal disease), hepatotoxicity

Question 4

Non-Steroidal Anti-Inflammatory Drugs: NSAID

flunixin meglumine (Banamine)

Answer 4

Inhibit cyclooxygenase and platelet aggregation

Horses, cows, pigs

Parenteral

GI ulcers, bleeding, renal necrosis (hypotension, dehydration, pre-existing renal disease), hepatotoxicity

Question 5

Non-Steroidal Anti-Inflammatory Drugs: NSAID

carprofen (Rimadyl)

Answer 5

Inhibit cyclooxygenase and platelet aggregation

Small Animal

Oral, parenteral

GI ulcers, bleeding, renal necrosis (hypotension, dehydration, pre-existing renal disease), hepatotoxicity

Question 6

Non-Steroidal Anti-Inflammatory Drugs: NSAID

meloxicam (Metacam)

Answer 6

Inhibit cyclooxygenase and platelet aggregation

Small animal

Oral, parenteral

GI ulcers, bleeding, renal necrosis (hypotension, dehydration, pre-existing renal disease), hepatotoxicity

Question 7

Antihistamines

Trimeprazine + prednisolone (Vanectyl-P)

Answer 7

Little Pink Pill

H1 antagonist

Used for:

• bronchoconstriction
• blood vessel dilation
• increased capillary permeability
• increased glandular secretion