Chapter 8: 8.3 Mitosis Flashcards
Mitosis
A process in which a cell divides into two identical “daughter” cells, which are genetically identical to each other as well as the “mother” cell
True or False:
Most cells of our body divide through mitosis
True
What is the purpose of mitosis?
- Growth
- Replace old and dying cells
What is the 5 phases of mitosis?
- Prophase
- Prometaphase
- Metaphase
- Anaphase
- Telophase
Mitosis:
Prophase
- Chromosomes start to condense
- Mitotic spindle formation
- Nucleolus disappears
Mitosis:
How does mitotic spindle formation occur in prophase?
- Centrosome forms mitotic spindle
Mitotic spindle
* Composed of microtubules
* Organize chromosomes
* Move them to appropriate locations during mitosis
* Gets longer as centrosomes move apart
Mitosis:
Prometaphase
- Chromosomes fully condensed
- Nuclear envelope breaks down
Mitosis:
In prometaphase, what happens to the mitotic spindle?
- Grows
- Begins to attach to the kinetochore of the chromosomes’ centromere
Mitosis:
Metaphase
- Chromosomes align at the metaphase plate
- Spindle checkpoint
Mitosis:
What is the spindle checkpoint in metaphase-anaphase?
Checks to ensure the chromosomes attach properly to each kinetochore
* Segregated properly before anaphase
Mitosis:
What does the chromosomes attach to in metaphase?
The 2 kinetochores of each chromosome are attached to microtubules
* 1 kinetochore per sister chromatid
* Each attached to an opposite centrosome
Mitosis:
Anaphase
- Sister chromatids separate and are pulled towards opposite ends of the cell
Mitosis:
What happens to the microtubules and chromosomes in anaphase?
- Microtubules that ARE NOT attached to chromosomes push apart
- Causes the cell to elongate + poles to move away from each other
Mitosis:
Telophase
- Cytokinesis begins
- Mitotic spindle is broken down
- A nucleolus forms in each side of the cell
- Nuclear membrane begins to form
- Chromosomes decondense
When does cytokinesis usually start?
Anaphase or Telophase