Chapter 75: Sulfonamide Antibiotics

Question 1

sulfonamides

Answer 1

Bactrim: sulfamethoxazole/trimethoprim ​

Very Broad Spectrum, (gram + and gram – and MRSA and some fungi) However multiple side effects. Resistance is wide spread​

Treats MRSA (good for CA) and UTI**

Question 2

sulfa ADR

Answer 2

Marrow Suppression​

Skin rashes​
Hypersensitivity (Sulfa Allergy); Steven Johnson Syndrome​. Early sign of SJS is erythema multiforme

Crystal urea​
Poorly soluble- urine crystals- can cause renal failure. Drink water!​

Photosensitivity​

H/A

insomnia​

Question 3

T/S therapeutic goal

Answer 3

Absence of Infection

Question 4

t/s baseline data

Answer 4

Blood and or urine cultures. CBC, renal function tests.

Question 5

t/s monitoring

Answer 5

CBC should be monitored if the patient develops signs or symptoms of blood disorders. S&S of hypersensitivity​

Question 6

identifying high risk pt t/s

Answer 6

Contraindicated in pregnancy and nursing mothers. Use cautiously in patient with renal impairment. Contraindicated when folate deficiency is likely (alcoholism and pregnancy) ​

Question 7

t/s evaluating effects

Answer 7

Monitor for reduction in bacterial symptoms: fever edema, pain, inflammation. Symptoms resolve​