Chapter 39: Calcium Channel Blockers Flashcards
CCB non dihydropyridine
Agent that affects the heart and Blood Vessel
Non-di good for tachydysrhytmias: afib, A flutter
Verapamil (Calan)
Diltiazem (Cardizem)
CCB hidyrophyridine
Agent that acts mainly on Blood Vessel
Used for HTN
Nifedipine (Procardia)
Amlodipine (Norvasc)
Nicardipine (Cardene)
Nimodipine (Nimotop)
CCB dihydro effect on SVR
decrease
CCB nondihydro effect on SVR
decrease (less than dihydros)
CCB dihydros intropy (effect on contractility), chronotropy (effect on SA node rate), and dromotropy (effect on AV node conduction)
no effect
CCB non-dihydro intropy
decreases
CCB non-dihydro chronotropy and dromotrophy
slows
CCB dihydro effect on conduction within the atria and ventricles
no clincally sigificant effect
CCB non-dihydro effect on conduction within the atria and ventricles
no clinically significant effect
non-dihydro MOA
Inhibits calcium, dilates coronary arteries and acts as Antidysrythmics
non-dihydro use
Angina, HTN, Cardiac Dysrhythmia (Atrial fib/flutter/ SVT conversion)
non-dihydro SE
flushing dizziness HA, hypotension, peripheral vasodilation (edema), constipation -often pair with stool softener so we don’t have them bearing down and VM
dihydro MOA
Inhibits calcium ion influx into vascular
smooth muscle and myocardium
dihydro use
Treatment of HTN, CAD, angina (variant)
Variat angina: coronary arteries spasm, if you give CCB, releases spasms. CCB treatment of choice
dihydro SE
flushing dizziness HA, hypotension, peripheral vasodilation (edema), constipation (less than nondi)
