Chapter 7 Translocations Flashcards
1
Q
Ewing Sarcoma
A
t11;22
2
Q
Chronic myelogenous leukemia (CML)
A
T(9;22)
3
Q
Acute myeloid leukemia (AML)
A
Known to be associated with DIC
T(8;21)
T(15;17)
4
Q
Acute promyelocytic leukemia (APML)
A
T(15;17)
5
Q
Burkitt lymphoma
A
T(8;14)
6
Q
Mantle cell lymphoma
A
T(11;14)
7
Q
Follicular lymphoma
A
T(14;18)
8
Q
Prostatic adenocarcinoma
A
T(7;21)
T(17;21)
9
Q
Retinoblastoma
A
Del (13q14)
10
Q
Von Hippel Lindau syndrome
A
Del (3p)
11
Q
T-cell acute lymphoblastic leukemia
A
Small deletion of chromosome 1
12
Q
Lung cancers
A
Deletions involving chromosome 5
EML4-ALK fusion gene
13
Q
MYC
A
T(8;14)
Burkitt lymphoma
14
Q
NMYC amplification
A
Chromosome 2p
Double minutes or as a chromosomally integrated homogenous staining region (HSR)
Neuroblastoma
15
Q
Chronic myelogenous leukemia
A
T(9;22)
ABL tyrosine kinase
