Chapter 7 Flashcards
The substance MPTP, which caused “instant Parkinson’s disease,” was a selective neurotoxin that killed cells in the __________.
basal ganglia
Which type of drug passes into the bloodstream from the intestines?
a. Drugs that are weak acids.
b. Drugs that are hydrophilic.
c. Drugs that are inhaled.
d. Drugs that are weak bases.
D. Drugs that are weak bases.
The drug Prozac interferes rather specifically with the reuptake of __________.
serotonin
What does the pineal gland have in common with the area postrema?
Both are unprotected by the blood-brain barrier.
Black widow spider venom causes the excess release of __________.
acetylcholine
Botulinum toxin blocks the release of __________.
acetylcholine
Which statement is NOT true of antidepressant drugs?
a. They have selective and very specific actions on the brain.
b. They improve chemical transmission in noradrenaline and histamine synapses.
c. It takes several weeks for their users to exhibit antidepressant effects.
d. Their use can result in increased anxiety and memory impairment.
A
Which kind of tolerance causes the body to create more enzymes to break a drug down?
metabolic
It is now believed that __________ is the neurotransmitter involved in drug addiction.
dopamine
Which is the best description of the hedonic hypothesis?
a. Addiction occurs because users take a drug to avoid unpleasant psychological withdrawal systems.
b. Addiction develops subconsciously as a result of conditioned learning.
c. Addiction is the result of users taking drugs that produce pleasure.
d. Addiction results from activity in the mesolimbic dopamine system.
C
The GABAA receptor has an ion channel specific to which ion?
a. Ca2+
b. Na+
c. K+
d. Cl-
D. Cl-
Most of the drugs used to treat schizophrenia block a receptor for __________.
dopamine
Cannabis seems to act on receptors for the neurotransmitter __________.
anandamine
Which neurotoxin blocks glycine?
strychnine
