chapter 68 (exam 2) Flashcards
what are oral findings suggestive of blood disorders?
gingival bleeding (in the oral soft tissue)
history of bruising easily
history of diff. in controlling bleeding
numerous petechiae
pallor of mucous membrane
atrophy of papillae of tongue
persistent sore or painful tongue (glossodynia)
acute or chronic infections (candidiasis)
severe ulcerations (lack of response)
exaggerated gingival response to local irritants
what is the composition of blood?
55% plasma fluid, 45% formed elements (erythrocyties (RBC), 1% leukocytes (wbc)
where do blood cells originate from?
bone marrow
what are the types of plasma proteins?
albumin- maintains tissue fluid pressure
gamma globulins- circulating antibodies
beta globulins- trasports hormones, metallic ions, and lipids
fibrinogen and prothrombin- blood clotting
these are biconcave discs containing hemoglobin that carries oxygen to the cells and carbon dioxide from the cells
red blood cells (erythrocytes)
what are the types of WBC?
agrunulocytes and granulocytes
what are the types of agranulocytes?
lymphocytes, monocytes (turn into macrophage)
what are granulocytes?
neutrophils, eosinophils and basophils
these are small round cell, can move back and forth bt vessels and tissues, and capable of reverting back and multiplying as immunologic need arises
lymphocytes
these are called polymorphonucluear leukocytes, most numerous of all WBC and first line of defense in the body
neutrophils
these increase during allergic conditions
eosinophils
these increase vascular permeability during inflammation so phagocytic cells can pass into the area
basophils
these are 1/4 size of RBC and are active in blood clotting mechanism
platelets
this means there is a reduction of the hemoglobin concentration, the hematocrit, or number of RBC is below the normal
anemia
what are the types of causes of anemia?
blood loss
increased hemolysis
diminished production of RBC
Chronic disease
genetic blood disorders
what are the clinical characteristics of anemia?
pale skin, nails and buccal mucosa.. weakness, malaise, fatigue, and dyspnea
this is when dietary intake is low, defective absorption from GI tract (pernicious anemia or B12), increased demand for nutrients
nutritional deficiency
this is aplastic anemia and occurs when bone marrow injured by medications, radiation, chemo, or infection
bone marrow failure
what are the characteristics of iron deficiency anemia?
hemoglobin deficient
rbc smaller
younger generation
diagnosis by lab test
what are the causes of iron deficiency anemia?
malnutrition or malabsorption chronic infection bariatic surgery increased demand of body of iron chronic blood loss internal bleeding
what are the oral signs and symptoms of iron deficiency anemia?
pallor of mucosa and weakness
atrophic glossitis with loss of filliform papillae
glossodynia (burning tongue)
angular chelitis
this type of anemia involves abnormally large RBC and can result in vitamin b12 deficiency or folate deficiency or both
megaloblastic anemia
this type of anemia occurs in pt over age of 60 and treat with b12 injections
pernicious anemia