Chapter 6 Integumentary System Flashcards
functions of skin
Protection (physical and Chemical
Regulation of body temperature
Contains sensory receptors
Excretion and absorption
Synthesis of Vitamin D
Stores Nutrients
How thichk is the integumentary system
what tissue types did the integumentary system contain
all 4
how large is the integumentary system
22 square feet
what are the two layers of the skin?
Epidermis and dermis
What tissue are the Epiderms made up of
Epithelial
What tissues are the dermis made up of
mostly connective, with some nerve, muscle, and epithelial
Subcutaneous tissue
a layer of adipose and areolar tissue (also known as hypodermis or subQ)
Characteristics of Epidermis
Mostly stratified squamous epithelium, it contains no blood vessels, 4 types of cells, 5 distinct strata (layer) of cells
What are the four types of cells in the epidermis
Keratinocytes, melanocytes, Langerhans cells, and Merkel cells
Keratinocytes
90% of the epidermis, made from stem cells of skin and produce keratin, which strengthens and waterproofs the skin.
Melanocytes
8% of the epidermis; produces the pigment melanin
Langerhan cell (dendritic)
Comes from bone marrow, and provides immunity
Merkel cells (tactile cells)
Found in the deepest layer (Basale layer) forms touch receptors with sensory neurons.
what are the 5 layers of the epidermis?
Corneum, Lucidum, Granulosum, Spinosum, Basale
Basale Layer
is the deepest layer of the epidermis, a single layer of cells, attached to the basement membrane, contains Merkel cells, melanocytes, and keratinocytes, it is the only are of cell division in the epidermis
Spinosum Layer
8 to ten layers of keratinocytes held together by desmosomes, these cells take in the pigment melanin by phagocytosis from nearby melanocytes, Langerhan cells found here help with immunity.
Granulosum layer
3-5 layers of flat dying keratinocytes, keritinization occurs as cells move upward
Keratinization
Nucleus and Organelles degenerate, cells fill with keratin and die
Lucidum Layer
Only found in thick skin (soles of feet and palms), 3-5 layers of clear, flat, dead cells
Corneum layer
25 to 30 layers of flat dead cells filled with keratin, acts as a barrier to light, heat, water, chemicals, and bacteria
what is produced when stem cells deivide
keratinocutes
keratinocytes are filled with what
keratin
how long does it take for cells to grow and be shed
4 weeks (2 to get to the corneum, 2 more before they shed)
Psoriasis
chronic skin disorder in which cells shed in 7-10 days as flakey silvery scales, abnormal keratin produced
Skin grafts
covering a wound with a piece of healthy skin
What would cause the need for skin grafts
damage of stem cells
Autograft
skin graft from self
isograft
skin graft from twin
Autologous skin
transplantation of skin from self, grown to size in a lab
How do melanocytes make melanin
By converting turosine to melanin
What increases melanin production
UV in sunlight
What causes freckles
a patch of melanocytes
Albanism
Lack of tyrosinase; no pigment
vitilligo
auto immune loss of melanocutes in areas of the skin, produces white patches.
where is Carotene found
in the stratum corneum and the dermis
What is Carotine
Yellow-Orange pigment (precursor of vitamin A)
If other pigments are not present epidermis is translucent so pinkness will be evident
Hemoglobin
Red, Oxygen carrying pigment in blood
Jaundice
Yellowing of the skin and whites of eyes, caused by buidup of yellow bilirubin in blood from liver disease
Cyanotic
Bluish color to nail beds and skin, hemoglobin depleted of oxygen looks purple-blue