Chapter 5: Structure and Function of Large Biological Molecules Flashcards
Macromolecules
Large polymers
Polymer
Long molecule consisting of many similar building blocks ex. Carbohydrates, proteins, nucleic acids
Monomers
Repeating units that serve as building blocks
Enzymes
Specialized macromolecules that speed up chemical reactions (mostly proteins)
Dehydration reaction
Two monomers bond together through the loss of a water molecule
Hydrolysis
Disassembly of polymers into monomers by use of breaking water molecules. (Opposite of dehydration reaction)
Carbohydrates
Sugars and polymers of sugars
Monosaccharides
Simple sugars, major fuel for cells ex. glucose
Polysaccharides
Polymers of sugars, storage = starch/glycogen, structural = cellulose/chitin
Disaccharide
Formed when dehydration reaction joins two monosaccharides
Glycosidic linkage
Covalent bond between two monosaccharides
Cellulose
Structural polysaccharide, In plant cell walls, beta glycosidic linkages
Chitin
Structural polysaccharide, alpha glycosidic linkages
Lipids
No true polymers, nonpolar, fats, phospholipids, and steroids
Fats
Glycerol and fatty acids, Esther linkages, used as energy storage and cushion
Saturated fats
All carbons linked by single bonds, solid at room temperature
Unsaturated fats
Contain one or more double bonds, tend to be liquid at room temperature
Phospholipid
Two fatty acids and a phosphate group attached to a glycerol
Steroids
Lipids characterized by a carbon skeleton consisting of four fused rings. Ex cholesterol, testosterone, estrogen
Proteins
Polymers of amino acids (monomers) in a specific sequence that are linked by peptide bonds
Polypeptide
A polymer of amino acids
Amino acids
Organic molecules with amino and carboxyl groups, and an R group
Primary structure
Unique sequence of amino acids
Secondary structure
Protein folding (alpha helix, beta pleated sheets) due to hydrogen bonding between the polypeptide backbone
Tertiary structure
Folding interactions between R groups give protein complex a 3D shape
Quaternary structure
Two or more polypeptide chains form one macromolecule
Denaturation
The loss of a proteins native structure
Nucleic acid
Made of monomers called nucleotides. Ex. DNA, RNA
Polynucleotide
Nucleotides linked together by phosphodiester linkages
Genomics
Analyzing large sets of genes or genomes
Proteomics
Analyzing large sets of proteins
Bioinformatics
Uses computer software and other computational tools to deal with data resulting from sequencing many genomes