Chapter 12: Cell Cycle Flashcards

1
Q

Types of cell division

A

Mitosis and meiosis

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2
Q

Mitosis

A

Division of somatic (non-reproductive) cells

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3
Q

Meiosis

A

Division of gametes (reproductive cells)

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4
Q

Genome

A

All the DNA inside of a cell
(One or many DNA molecules)

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5
Q

Chromosome

A

Package of DNA molecules in a cell

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6
Q

Chromatin

A

Complex of DNA and proteins that condenses during cell division

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7
Q

Diploid

A

2 sets of chromosomes (2n)

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8
Q

Haploid

A

One set of chromosomes (n)

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9
Q

Somatic cells

A

Non-reproductive cells

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10
Q

Gametes

A

Reproductive cells (sperm and ovum/eggs)

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11
Q

Sister chromatids

A

Joined copies of an original chromosome

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12
Q

Centromere

A

Narrow “waist” of a duplicated chromosome

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13
Q

Cytokinesis

A

Division of the cytoplasm

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14
Q

Interphase

A

Period of cell growth and chromosome duplication before mitosis

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15
Q

G1 phase

A

Gap 1 (Cell growth, protein and organelle production)

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16
Q

S phase

A

Synthesis (chromosome duplication/ DNA replication)

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17
Q

G2 phase

A

Gap 2 (cell growth and preparation for mitosis)

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18
Q

Mitotic spindle

A

Microtubule structure that controls chromosome movement during mitosis

19
Q

Centrosome

A

Microtubule-organizing center

20
Q

Kinetochore

A

Protein complex associated with the centromere

21
Q

Metaphase plate

A

Imaginary plane midway between the spindle’s two poles

22
Q

Prophase

A

Chromatin condenses, nucleus disappears,
spindles form

23
Q

Metaphase

A

Chromosomes line up on the metaphase plate, centromeres on opposite poles

24
Q

Anaphase

A

Sister chromatids separate, chromosomes are pulled to poles

25
Q

Telophase & Cytokinesis

A

Chromosomes condense, nucleus reforms, cytoplasm pinches

26
Q

Cleavage

A

Process of dividing the cytoplasm

27
Q

Cell plate

A

A cell wall formed between two duplicated plant cells

28
Q

Binary fission

A

Prokaryotic cell division

29
Q

Origin of replication

A

Beginning of chromosome replication during binary fission

30
Q

Cell cycle control system

A

Regulatory clock with checkpoints that controls the cell cycle

31
Q

Checkpoints

A

Points in which the cell cycle stops until a go-ahead signal is given

32
Q

Cyclin

A

Regulatory protein that fluctuates in concentration throughout the cycle

33
Q

Cyclin-dependent kinase (CDK)

A

Regulatory protein that binds with cyclin and who’s activity rises with its concentration

34
Q

Maturation-promoting factor (MPF)

A

Cyclin-CDK complex that triggers a cell’s passage past the G2 checkpoint into the M phase

35
Q

G0 phase

A

Non-dividing state reached when the go-ahead signal is not received by a cell

36
Q

Growth factors

A

Proteins released by certain cells to stimulate other cells to divide

37
Q

Density-dependent inhibition

A

Crowded cells stop dividing

38
Q

Anchorage dependence

A

Cells must be attached to a substratum in order to divide

39
Q

Transformation

A

Acquiring the ability to divide indefinitely

40
Q

Tumor

A

Mass of abnormal cells within otherwise normal tissue

41
Q

Benign tumor

A

Abnormal cells remain only at original site

42
Q

Malignant tumor

A

Abnormal cells that invade surrounding tissues

43
Q

Metastasize

A

When cancer cells spread to other parts of the body forming additional tumors