Chapter 5 Flashcards

(41 cards)

1
Q

What is metabolism?

A

combined catabolic and anabolic reactions in a body

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2
Q

What is catabolism?

A

breaking down molecules and releasing energy

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3
Q

What is anabolism?

A

synthesizing molecules and NEEDS energy

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4
Q

Is glycolysis anaerobic or aerobic?

A

anaerobic

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5
Q

What is glycolysis?

A

pathway where glucose is converted into 2 pyruvates

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6
Q

What is the net equation for glycolysis?

A

glucose + 2 NAD + 2 ADP + 2Pi -> 2 pyruvates + 2 NADH + 2 ATP

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7
Q

Is glycolysis exergonic or endergonic?

A

exergonic
- produces energy

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8
Q

Why does the reaction begin with glucose turning into G6P?

A

phosphorylation traps glucose inside cell

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9
Q

What is the ATP exchange in glycolysis?

A

uses 2 ATP to make 4 ATP

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10
Q

Why do we need to make lactic acid?

A

to avoid end-product inhibition
- NADHs produced in glycolysis needs to give hydrogens away

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11
Q

How does lactic acid pathway work?

A

without oxygen, NADH gives hydrogens to pyruvate to make lactic acid

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12
Q

What is the net gain in the lactic acid pathway?

A

2 ATPs per glucose

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13
Q

What blood cell only uses lactic acid pathway? Why?

A

red blood cells
- no mitochondria

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14
Q

Where does the lactic acid pathway occur?

A

skeletal and heart muscle when oxygen supply falls below critical level

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15
Q

How is glucose stored?

A

as glycogen (long glucose chains)

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16
Q

What is glycogenolysis?

A

clips glucose out of glycogen as G6P

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17
Q

What is the only organ that can remove phosphate groups?

A

liver has glucose-6-phosphatase and can secrete glucose

18
Q

What is the cori cycle?

A

lactic acid -> pyruvate -> glucose and glycogen
- gluconeogenesis (reverse glycolysis)

19
Q

How does aerobic respiration start?

A

pyruvate enters mitochondria
- CO2 clipped off pyruvate to form acetyl CoA

20
Q

How does Krebs Cycle start?

A

acetyle CoA combines with oxaloacetate to make citrate

21
Q

What does the Krebs Cycle produce?

A

1 GTP, 3 NADH, 1 FADH2

22
Q

How does FADH2 and NADH get converted to energy (ATP)?

A

by carrying electrons to the electron transport chain

23
Q

What proteins are involved in the ETC?

A

FMN, coenzyme Q and cytochromes

24
Q

Where does ETC occur?

A

cristae of mitochondria

25
Is ETC endergonic or exergonic?
exergonic - energy is used to phosphorylate ADP to make ATP (oxidative phosphorylation)
26
How does the ATP synthase work?
- energy gathered from ETC pumps H+ into mitochondrial outer chamber (high H+ concentration) - H+ diffuses down concentration and charge gradient and back into their inner chamber
27
What is the chemiosmotic theory?
how ETC work and how the energy released by the transfer of electrons to create an electrochemical gradient across a membrane
28
What happens to the electrons added to ETC?
reaches the end and O2 accepts them to make water
29
What are the 2 ways ATP is made?
1) Direct (substrate-level) phosphorylation - 2 ATP in glycolysis - 2 ATP in Krebs 2) Oxidative phosphorylation in Krebs cycle (ETC) - 30-32 ATPs
30
How many ATP is made in ETC?
3 (or 4) H+ forms 1 ATP - makes 26 ATP
31
How many ATP is made from NADH? FADH2?
1 NADH = 3 ATP 1 FADH2 = 2 ATP
32
What is the total ATP production?
26 ATP from ETC 2 ATP from glycolysis 2 ATP from Krebs = 30 ATP/glucose
33
How are fats used as energy?
hydrolyzed to glycerol and fatty acids
34
How can proteins be used as energy?
broken down to amino acids - can be deaminated and r=
35
What is acetyl CoA?
substrate for energy and synthetic pathways
36
What is fat? (triglycerides)
fatty acid + glycerol
37
What is the main form of energy storage?
fat - 9 kcal/g
38
What is lipolysis?
breakdown of fat into fatty acids and glycerol - hydrolysis
39
What is beta-oxidation?
clips acetyl CoA off of fatty acid chains
40
What is transamination?
interconverts amino acids
41
What is deamination?
removes amino group