Chapter 4.7 - Tissue repair Flashcards
What is needed for tissue reapir?
It requires cell division and migration initiated by hrowth factors released by injured cells and an inflammatory process
What are the two major ways tissue repair can occur
Regeneration: same kind of tissue replaces destroyed tissue
Fibrosis: connective tissue (scar tissue)
What happens in inflammation sets the stage?
release of inflammatory chemicals causes: dilation of blood vessels and increase in blood vesselo permeability and clotting of blood occurs
When starts organization?
When the blood clot is replaced with granulation tissue
erefor is organization?
It restores blood supply
What happens in the organization step?
Fibroblasts produce collagen fibers to bridge the gap until regeneration is complete, eptihelikum begins to regenerate, any debris in area is phagocytized
What happens int he regeneration and fibrosis effect permanent repair step?
the scab detaches
fibrous tissue matures
epithelium thickes and begins to tesemble adjacent tissue
results in a fully regenerated epithelium with underlying scar tissue which may or may not be visible
What happens int he regeneration and fibrosis effect permanent repair step?
the scab detaches
fibrous tissue matures
epithelium thickes and begins to tesemble adjacent tissue
results in a fully regenerated epithelium with underlying scar tissue which may or may not be visible
What tissues regenerate extremely well?
Epithelial tissue, bone, areolar connective tissue, dense irregulare connective tissue, blood forming tissue
What are tissues with moderate regenerating capacity?
Smooth muscle and dense regular connective tissue
What is tissue with weak regenerating capacity?
Skeletal muscle and cartilage
Tissue with no functional regenerative capacity?
Cardiac muscle, nervous tissue of brain and spinal cord
