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343 Pharm Exam 2 > Chapter 44 Antihyperlipidemics & Drugs To Improve Peripheral Blood Flow > Flashcards

Chapter 44 Antihyperlipidemics & Drugs To Improve Peripheral Blood Flow Flashcards

1
Q

What is HDL?

A

Good cholesterol

Transportto liver for elimation

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2
Q

What is LDL cholesterol?

A

Bad cholesterol!

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3
Q

What is VLDL?

A

Mostly triglycerides
No cholesterol

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4
Q

What is chylomircons?

A

Transport fatty acids and cholesterol to liver

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5
Q

What are some nonpahrmacologic methods for reduction of cholesterol?

A

Stop smoking
Reduce salt
Reduce fats
Reduce cholesterol intake 300mg a day
Exercise

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6
Q

What are the types of antihyperlipidemics?(5$

A

Bile acids sequestranrs
Fibric acid
Nicotonic acid
Cholesterol absorption inhibitor
Statins

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7
Q

How does bile acid sequestranrs help cholesterol?

THIS BINDS TO EVERY OTHER MEDICATONS!!
TAKE AN HOUR OR TWO LATER OR BEFORE !!

A

Reduce LDL levels by binding with bile acids in the stomach

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8
Q

What are the 3 side effects of bile acid sequestrants?

A

Constipation
Flatulence
Steatorrhea

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9
Q

What is fibrates?
Contraindicated with what?
Side effect?

A

Reduces trig and VLDL
Anticoagulants = bleeding

Dizzy, cholethiasis

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10
Q

What does niacin do?

Biggest side effect?

A

B vitamin, larger dose to achieve cholesterol lowering

Flushing

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11
Q

IGNORE THIS!!!

Wuat does cholesterol absorption inhibitor do?

Must be combined with what to be fully absorbed?

A

Acts in cells in the small intentions and blocks cholesterol absorption

Statin

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12
Q

What does statins do?

Is it the first line treatment?

Side effects ? (2)

A

Inhibit the enzyme HMG COA in cholesterol

Yes

Rhabdomyolysis & muscle cramps
( muscle cramps, break down muscle )

( patients wil say I’m still sore after a weekend, super SORE!!! More than normal )

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13
Q

What should you avoid with stains?

A

Grapefruit juice

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14
Q

Statins increase toxicity in what?

A

Digoxin!!

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15
Q

What do you want to monitor for statins??

A

Creatine kinase & LFTS

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16
Q

Statins increase the effects if birth control, but a huge risk for?

A

Blood clots

17
Q

When homocysteine and c reactive protein elevated you are at greater risk for?

4-17 normal

A

Negative cardiac events
Heart attack
Stroke

18
Q

How long do you check cholesterol levels?

A

3 months

19
Q

PVD is treated with what?(2)

Make sure there pulses are okay
Temp of skin
Pulses are equal
No alcohol
Change position slowly

A

Blood pressure meds
And statins

343 Pharm Exam 2 (9 decks)

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