Chapter 43 & 44 Diseases Of The Peripheral Nerves and Cranial Nerves Flashcards
Connective tissue covering of individual nerve fibers
A. Epineurium
B. Endoneurium
C. Perineurium
D. Mesoneurium
B. Endoneurium
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Described as “dying forward” phenomenon in which the nerves degenerates fromo the point of axonal damage outward.
A. Segmental Demyelination
B. Wallerian Degeneration
C. Axonal Degeneration
D. Chromatolysis
B. Wallerian Degeneration (page 1312)
Dying Back phenomenon
A. Segmental Demyelination
B. Wallerian Degeneration
C. Axonal Degeneration
D. Chromatolysis
C. Axonal Degeneration (page 1312)
Meningoradiculitis of the posterior roots, mainly lumbosacral segments
A. Diphtheria B. PAN C. Tabes Dorsalis D. Doxorubicin Toxicity E. Arsenic F. Vincristine Toxicity
C. Tabes Dorsalis
Essential lesion in GBS A. Increase in CSF protein B. Edema of the nerve roots C. Perivascular mononuclear inflammatory infiltration of the roots of and nerves D. Absence of inflammatory infiltrates
C. Perivascular mononuclear inflammatory infiltration of the roots of and nerves
Focal Degeneration of the myelin sheath with sparing of the axon A. Segmental Demyelination B. Wallerian Degeneration C. Axonal Degneration D. All of the above
A. Segmental Demyelination
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Earliest Symptom of GBS A. Paresthesias in the toes and fingers B. Symmetric weakness C. Cranial Nerve involvement D. Pain in muscles
A. Paresthesias in the toes and fingers
Earliest immunologic event in GBS
A. Complement deposition on the myelin surface
B. Production of antibodies against myelin
C. Antigen-antibody reaction
D. None of the above
A. Complement deposition on the myelin surface
Variant of GBS associated with ANTI-GM1 A. Pure Sensory B. Pure Motor C. Pandysautonomia D. Axonal (AMAN)
D. Axonal (AMAN)
P.1322
Variant of GBS associated with anti-GQ1b? A. Ophtalmoplegia B. Oculopharyngeal weakness C. Cervico-brachial-pharyngeal weakness D. Bilateral facial or abducens weakness
A. Ophthalmoplegia
Variant of GBS associated with anti-GT1a? A. Ophthalmoplegia B. Oculopharyngeal weakness C. Cervico-brachial-pharyngeal weakness D. Bilateral facial or abducens weakness
C. Cervico-brachial-pharyngeal weakness
Acute relapsing predominantly motor neuropathy with an early bibrachial distribution of weakness and with truncal sensory loss, accompanied by abdominal pain, psychotic symptoms and trachycardia? A. Porphyric polyneuropathy B. Organophosphate polyneuropathy C. TOCP polyneuropathy D. Thallium polyneuropathy E. Arsenic Polyneuropathy
A. Porphyric polyneuropathy
Nerve that passes in the cubital tunnel
A. Median Nerve
B. Ulnar Nerve
C. Radial Nerve
D. All of the above
B. Ulnar Nerve
The following statements are true regarding peripheral nerves, EXCEPT:
A.
B. The structure of the axonal membrane in the gaps between segments of myelin sheaths is specialized, containing high concentration of Na channels
C. myelinated fibers are more numerous in peripheral nerves than unmyelinated ones
D.
C.
-unmyelinated fibers are more numerous than unmyelinated ones in the PNs
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Miller fisher Variant of GBS may be associated with this antibody?
Anti GQ1B
Pathology of arsenic neuropathy
A. Wallerian degeneration
B. Axonal Degeneration
C. Segmental Demyelination
B. Axonal Degeneration
The following statements are true regarding acute diabetic mononeuropathies, EXCEPT:
a. diabetic ophthalmoplegia usually presents as isolated painful 3rd nerve palsy with involvement of pupillary function
b. occasionally, the 6th cranial nerve may be involved unilaterally
c. the most frequently involved peripheral nerves in acute diabetic mononeuropathies are the femoral, sciatic and peroneal nerves
d. acute diabetic mononeuropathies of the cranial and peripheral nerve are presumably a result of infarction of a nerve
a. diabetic ophthalmoplegia usually presents as isolated painful 3rd nerve palsy with involvement of pupillary function
ANS
should be with SPARING of the pupillary function.
Findings of c-ANCA is associated with which vasculitic neuropathy?
(Give 2)
Wegener granulomatosis
And
Eosinophilic granulomatosis with polyangiitis (Churg-Straus)
Findings of p-ANCA is associated with which vasculitic neuropathy
Polyarteritis Nodosa
Triad of symptoms of Lyme neuropathies
- Cranial nerve palsies
- Radiculitis
- Aseptic meningitis
A slow and progressive autoimmune disease characterized by lymphocytic infiltration of exocrine glands particularly the parotid and lacrimal glands.
Sjogren Disease
Infraclavicular lesion involving the cords of the brachial plexus presenting as weakness of the deltoid muscles, extensors of the elbow, wrist and fingers and sensory loss of the outer surface of the upper arm
A. Lateral cord
B. Medial Cord
C. Posterior cord
c. posterior cord
Infraclavicular lesion involving the cords of the brachial plexus presenting as weakness of flexion and pronation of the forearm
A. Lateral cord
B. Medial Cord
C. Posterior cord
A. Lateral cord
Lesion of the cranial nerve 10 would present with weakness of the drooping of the soft palate on the
[ipsilateral/contralateral] side?
The uvula often deviates to the
[normal side/affected side] on phonation.
ipsilateral
normal side
T/F
the cranial nerve 11 or spinal accessory nerve is a purely motor nerve of cranial origin
F
the CN 11 is of spinal origin arising from the anterior horn cells of the upper 4 and 5 cervical segments
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The radial nerve branches from the _______ of the brachial plexus
a. posterior cord
b. medial cord
c. lateral cord
d. anterior cord
a. posterior cord
Most common site of injury of the radial nerve
Spiral groove
Paraprotein most commonly associated with polyneuropathy
a. IgG
b. IgM
c. IgE
d. IgA
b. IgM
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