15 Epilepsy and Other Seizure Disorders Flashcards
During the tonic phase of seizures, the following may occur except:
A. piercing cry
B. dilated pupils and unreactive to light
C. constricted pupils and unreactive to light
D. breathing is suspended
E. cyanosis of lips
F. None of the above
C. Constricted pupils…
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The following may occur during the clonic phase of seizures except
A. elevated blood pressure, rapid pulse rate
B. dilated pupils
C. Salivation and sweating are prominent
D. increased bladder pressure
E. apnea
F. none of the above
F. none of the above
Triad of West syndrome? (3)
- infantile spams
- hypsarrhythmia
- mental retardation
EEG findings of Typical Absence
3 hz spike and wave pattern
Drug of choice for Juvenile Myoclonic Epilepsy (JME)
Valproic acid
p 337
Second choice drug for JME for women with child bearing age
Levetiracetam
p. 337
Localization of Jacksonian seizures (focal motor) A. Superior temporal B. Prerolandic C. Contralateral post rolandic D. Frontal
B. Prerolandic
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Localization: auditory auras A. Heschl gyri B. Superior temporal C. Mesial temporal D. Insula
A. Heschl gyri
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Localization: olfactory auras A. Heschl gyri B. Superior temporal C. Mesial temporal D. Insula
C. Mesial Temporal
p 338
Localization: gustatory auras A. Heschl gyri B. Superior temporal C. Mesial temporal D. Insula
D. Insula
p 338
Localization: automatism (ictal and post ictal) A. Frontal B. Temporal C. Insula D. A and B E. B and C
C. A and B
frontal and temporal
p 338
Localization: masticatory, salivation and speech arrest in seizure A. supplementary motor cortex B. amygdaloid nuclei C. Prerolandic gyrus D. Heshcl gyri
B. Amygdaloid nuclei
p 338
Localization: formed hallucinations A. Temporal neocortex, or amygdaloid-hippocampal complex B. Frontal C. Mesial temporal D. Supplementary motor
A. Temporal neocortex, or amygdaloid-hippocampal complex
p. 338
Localization: visceral: autonomic A. Mesial Temporal B. amygdaloid-hippocampal complex C. Insula D. Insular-orbito-frontal cortex
D. Insular-orbito-frontal cortex
p 338
Localization: head and eye turning associated with arm movement or athetoid dystonic postures
A. Temporal neocortex, or amygdaloid-hippocampal complex
B. Frontal
C. Mesial temporal
D. Supplementary motor cortex
D. Supplementary motor cortex
p 338
Localization: vertiginous aura A. Superior temporal B. Mesial temporal C. Insula D. Insular-orbito-frontal cortex
A. Superior temporal
p 338
Most frequent reported color in visual seizures A. Blue B. Red C. Green D. Yellow
B. Red
Main treatment for children with GLUT1 deficiency syndrome
Ketogenic diet
The following medications can cause seizures, except:
a. bupropion
b. linezolid
c. lidocaine
d. lithium
e. none of the above
e. none of the above
Most common histologic finding in Mesial temporal sclerosis
loss of neurons in CA1 segment (Sommer Sector) of the pyramidal cell layer of the hippocampus
This antiepileptic medication acts through enhancement of slow inactivation of voltage gated sodium channels
lacosamide
Purple glove syndrome is associated with this AED?
phenytoin
Which of the following is the main mechanism of action of ethosuxamide?
a. Sodium channel inhibition
b. NMDA inhibition
c. T-type calcium channel inhibition
d. GABA potentiation
e. AMPA inhibition
c. T- Type calcium channel inhibition
According to the EURAP study, about _____ of epileptic women who become pregnant have no change in seizure frequency or severity.
a. 2/3
b. 1/3
c. 1/2
d. 1/4
a. 2/3
Dravet syndrome is associated with a loss of function mutation in this gene
SCN1A (sodium channel gene)
Protein involved in dentatorubropallidoluysian atrophy with PME
atrophin-1
A common focal motor epilepsy of childhood that is self limiting despite a very abnormal EEG pattern
Benign Epilepsy of Childhood with centrotemporal spikes
Post ictal nose wiping occurs in half of patients with seizures involving the
A. Frontal lobe
B. Temporal lobe
C. Occipital lobe
D. All of the above
B. Temporal lobe