Chap 2 Diagnostic Testing In Neurologic Disease

Question 1

Normal CSF pressure in children?

a. 100-180 mmH20
b. 30-60 mm H20
c. 60-100 mmH20
d. 80-100 mmH20

Answer 1

b. 30-60 mmh2o

p 15

Question 2

Major immunoglobulin in the normal CSF

Answer 2

IgG

Question 3

Special marker, (specific protein) in CSF when elevated is associated with prion disease

Answer 3

14-3-3 protein

Question 4

Special marker, (specific protein) in CSF when elevated is associated meningeal lymphomatosis

Answer 4

B2-microglobulin

Question 5

normal protein content of the lumbar CSF

Answer 5

45-50 mg/dl

Question 6

protein content of the CSF from the basal cistern

Answer 6

10-25 mg/dl

Question 7

protein content of the CSF from the ventricles

Answer 7

5-15 mg/dl

Question 8

During subarachnoid hemorrhage or traumatic tap, one would expect and increase in CSF protein by:

a. 1 mg/100 RBCs
b. 1mg/1000 RBCs
c. 10mg/100 RBCs
d. 10mg/1000 RBCs

Answer 8

b. 1 mg / 1000 RBCs

Question 9

In Magnetic Resonance Spectroscopy:
this cellular metabolite is considered a marker of neuronal integrity. It is decreased in both destructive lesions and in circumstances in which there is a reduction in the density of neurons (edema, glioma)

Answer 9

N-acetyl aspartate (NAA)

Question 10

This cellular metabolite is a marker of membrane turnover and is elevated in some rapidly dividing tumors seen in MRS

Answer 10

Choline