Chapter 42: Fluid and Electrolytes Flashcards
Body fluids contain
electrolytes such as Na+ and K+, and also have a certain degree of acidity
Fluid, electrolyte and acid-base balances within the body maintain
the health and function of all body sytems
The characteristics of body fluids have
regulatory mechanisms that keep them in balance
Characteristics of body fluids include
- fluid amount (volume)
- concentration (osmolarity)
- composition (electrolyte concentration)
- acidity (pH)
Body fluid
water that contains dissolved or suspended substances such as glucose, mineral salts and proteins
Approximately ____ of an adult male’s body weight is water…. decreasing to ____ in older men
60%
50%
Women have _____ water than men
less (less muscle mass, more adipose)
Why do obese people have less water than lean people?
fat contains less water than muscle
Extracellular Fluid
outside the cells.
in adults, this accounts for 1/3 of total body water.
ESF has 2 major divisions and 1 minor division, what are they?
- intravascular fluid
- interstitial fluid
- transcellular fluid (minor)
Intravascular fluid
liquid portion of the blood (plasma)
Interstitial fluid
located in-between the cells and outside the blood vessels
Transcellular fluid
cerebrospinal, pleural, peritoneal, and synovial fluids (secreted by epithelial cells)
Intracellular Fluid
inside the cells.
in adults, this accounts for 2/3 of the total body water.
electrolytes
a compound that seperates into ions (charged particles) when dissolved in water
2 types of electrolytes
cations and anions
cations
+ charge (Na+, K+, Mg++)
anions
- charge (Cl-, HCO3-)
Types of Solutions
- isotonic
- hypertonic
- hypotonic
isotonic
the molecular concentration of dissolved solutes is the same on both sides of the cell membrane (NS=0.9% sodium)
hypertonic
contains more dissolved particles (Na+ and other electrolytes) than is found in normal cells.
water is pulled out of cells (3-5% NaCl)
hypotonic
contains less solute (salt and other electrolytes) than is found in normal cells
water is pulled into the cell (.45NS)
What are the ways in which water and electrolytes move in and out of a cell?
- active transport
- diffusion
- osmosis
- filtration
Active Transport
Requires energy in the form of ATP to move electrolytes across cell membranes against the concentration gradient going from low to high concentration (giving it what the cell needs) .
Example: Sodium-Potassium pump
What electrolytes have a higher concentration in the ICF?
K+, mg++, and PO43−
What electrolytes have a higher concentration in the ECF?
Na+, Cl−, HCO3
Diffusion
Passive movement of SOLUTES from areas of higher to lower concentrations
Osmosis
WATER that moves through a membrane that separates fluids with different particle concentrations.
Osmotic Pressure
(ICF or Interstitial) inward pulling force from the particles in a fluid
Filtration
Fluid and solutes moving into and out of capillaries between vascular and interstitial compartments due to hydrostatic pressure.
Edema
accumulation of excess fluid in the interstitial space
Heart failure
causes venous congestion from a weakened heart which increases capillary hydrostatic pressure causing EDEMA (transudate) by moving excess fluid into the interstitial space.
Conditions that can cause edema
heart failure and inflammation
inflammation
(exudate) increases capillary blood flow and allows capillaries to leak colloids (proteins) into the interstitial space = increased capillary hydrostatic pressure and increased interstitial colloid osmotic pressure = localized edema in the inflamed tissue
Fluid Intake and Absorption
occurs orally, IV or irrigation where fluid is absorbed.
normally daily intake around 2300 ml/day
Fluid Distribution
Movement of fluid among its various compartments (ECF vs. ICF, Interstitial (between cells, outside blood vessels) vs. Vascular)
Fluid can be removed from the body through
- skin
- lungs
- GI tract
- kidneys
How is fluid removed through the skin?
sensible/insensible loss (perspiration)
How is fluid removed through the lungs?
insensible loss (breathing)
How is fluid removed through the GI tract?
stool (normally only 100 ml/day) and digestion
How is fluid removed through the kidneys?
urine secretion
Abnormal fluid output includes
diarrhea, vomiting, wound drainage, or hemorrhage
Antidiuretic Hormone
influences how much water is excreted in the urine
Renin-Angiotensin-Aldosterone System
Regulates ECF volume by influencing how much Na+ and water are excreted in urine.
Also contributes to regulation of BP.
Aldosterone also contributes to
electrolyte and acid-base balance by increasing urinary excretion of K+, and hydrogen ions
Fluid Imbalances include
- volume imbalances
2. osmolarity imbalances
Volume Imbalances
disturbances in the amount of fluid in the EC compartment
hypovolemia & hyervolemia
hypovolemia
decreased vascular volume
hypervolemia
increased vascular volume
Osmolarity Imbalances
disturbances of the concentration of body fluids
hypernatremia & hyponatremia
hypernatremia
water deficit.
when interstitial fluid becomes hypertonic (increased Na+) water leaves the cells by osmosis.
S&S of hypernatremia includes
cerebral dysfunction=confusion.