Chapter 41 Flashcards
Osmotic Laxatives examples
Magnesium hydroxide (MOM) Magnesium citrate
Osmotic Laxatives side effects
↑Mg level, dehydration
Bulk-Forming Laxatives contraindications
opiod use
Psyllium (Metamucil) category
Bulk-Forming Laxatives
Stool Softeners examples
Docusate sodium
Docusate calcium
(colace)
Lactulose use
Pulls water into intestine
Used for constipation and to remove ammonia in pt with liver disease
diphenoxylate with atropine (Lomotil) category
Opioid Antidiarrheals
Inflammatory Bowel Disease (IBD) components
Ulcerative colitis
Crohn’s disease
Inflammatory Bowel Disease (IBD) symptoms
Abdominal cramping and diarrhea
Crohn’s disease
ulceration in distal part of small intestine
Ulcerative colitis
erosions in large intestine
Mild-to-moderate IBD tx
with 5-aminosalicylic acid (5-ASA) agents
Persistant IBD tx
corticosteroids
Severe IBD tx
immunosuppresants
Crohn’s disease tx
Adalimumab (Humira™)
Adalimumab (Humira™) action
Neutralizes the activity of tumor necrosis factor which causes inflammation
Adalimumab (Humira™) adverse effects
flu-like sx, rash, erythema, pruritus, bleeding/hemorrhage pain or swelling, headache, erythema multiforme, Stevens-Johnson syndrome
Irritable Bowel Syndrome (IBS) symptoms
abdominal pain, cramping, bloating, gas
Constipation, alternating with diarrhea
Phenothiazine
can cause the adverse effect EPS (difficulty speaking)
Give Benadryl 25mg IV
Antihistamines action for N/V
blocking action of acetylcholine
Dopamine Antagonists
Block dopamine receptors in CTZ
Dopamine Antagonists ending
zine
Butyrophenones (Haldol, Droperidol) category
Dopamine Antagonists
Dopamine Antagonists adverse effects
EPS hypotension tremors restlessness do not give with cardiac issues
Benzodiazepines use
control N&V associated with chemo
use in combination with glucocorticoid & serotonin 5-HT3 receptor antagonist
Serotonin (5-HT3) Receptor Antagonists
most effective with chemo related N/V
Serotonin (5-HT3) Receptor Antagonists ending
setron
Serotonin (5-HT3) Receptor Antagonists benefits
do not cause EPS
Serotonin (5-HT3) Receptor Antagonists adverse effects
H/A, diarrhea, dizziness, fatigue
Serotonin (5-HT3) Receptor Antagonists route
PO or IV
Glucocorticoids use
chemo-induced nausea
Glucocorticoids ending
sone
Glucocorticoids side effects
so many side effects but none likely from one dose
cushing’s symptoms
Cancer Induced N&V cocktail
Decadron, Ativan, & 5HT3 receptor antagonists
Ipecac absorption causes
cardiotoxicity
Pancreatitis causes
gallstones in women
alcoholism in men
Pancreatitis symptoms
Severe pain- board like abdomen
