Chapter 4 - Tissues Flashcards
Collections of specialized cells and the extracellular substances surrounding them
Tissues
Body tissues are classified into:
4 types
structure of the cells
composition of the noncellular substances surrounding the cells (called
the extracellular matrix)
functions of the cells
The four primary tissue types:
epithelial tissue
connective tissue
muscle tissue
nervous tissue
the microscopic study of tissues
Histology
the process of removing
tissue samples from patients surgically or with a needle for diagnostic purposes.
biopsy
an examination of the organs of a
dead body to determine the cause of death or to study the changes caused by a disease.
autopsy
-blast means?
bud or germ
Approximately 13 or 14 days after fertilization, the embryonic stem cells that give rise to a new individual form a slightly elongated disk
consisting of two layers:
epiblast
hypoblast
Cells of the epiblast then migrate
between the two layers to form the three embryonic germ layers:
ectoderm
mesoderm
endoderm
give rise to all the tissues of the body
The germ layers
the inner layer, forms the lining
of the digestive tract and its derivatives.
endoderm
the middle layer, forms tissues such as muscle, bone, and blood vessels
mesoderm
the outer layer, forms the skin.
ectoderm
the portion of the ectoderm called __ becomes the nervous system
neuroectoderm
the groups of cells that break away from the neuroectoderm during development that give rise to parts of the peripheral nerves, skin pigment, the medulla of the adrenal gland, and many tissues of the face.
neural crest cells
covers and protects surfaces, both outside and inside the body
Epithelial tissue, or epithelium
characteristics common to most types of epithelial tissue:
- Mostly composed of cells.
- Covers body surfaces.
- Distinct cell surfaces.
- Cell and matrix connections.
- Nonvascular.
- Capable of regeneration.
where cells are exposed and not
attached to other cells.
free, or apical surface
where cells are attached to other epithelial cells.
lateral surface
attached to a basement membrane.
basal surface
often lines the lumen of ducts, vessels, and cavities.
free surface
a specialized type of extracellular material secreted by epithelial and connective tissue cells.
basement membrane
Functions of Epithelial Tissues:
- Protecting underlying structures.
- Acting as a barrier.
- Permitting the passage of substances.
- Secreting substances.
- Absorbing substances.
Classification of Epithelial Tissues based on the number of cell layers in each:
- Simple epithelium
- Stratified epithelium
- Pseudostratified columnar epithelium
single layer of cells, with each
cell extending from the basement membrane to the free surface.
Simple epithelium
consists of more than one layer of
cells, but only the basal layer attaches the deepest layer to the
basement membrane.
Stratified epithelium
pseudo- means?
false
this type of epithelium appears to be stratified but is not. It consists of one layer of cells, with all the cells attached to the basement
membrane.
Pseudostratified columnar epithelium
three types of epithelium based on idealized shapes of the epithelial cells:
- Squamous
- Cuboidal
- Columnar
cells are flat or scalelike
Squamous
cells are cube-shaped—about as wide as
they are tall.
Cuboidal
(tall and thin, similar to a column) cells tend to be taller than they are wide
Columnar
consists of one layer of flat, or
scalelike, cells that rest on a basement membrane
Simple squamous epithelium
consists of several layers of cells.
Near the basement membrane, the cells are more cube-shaped, but at the free surface the cells are flat or scalelike
Stratified squamous epithelium
are columnar in shape (taller than they
are wide) and, although they appear to consist of more than one layer, all the cells rest on the basement membrane
Pseudostratified columnar epithelial cells
Roughly cuboidal to columnar
when not stretched and squamouslike when stretched
Transitional epithelium
S: Single layer of flat,
often hexagonal cells
F: Diffusion, filtration,
some secretion, and some
protection against friction
L: Lining of blood vessels
and the heart, lymphatic vessels etc. (kidney)
Simple Squamous Epithelium
S: Single layer of cube shaped cells.
F: Secretion and
absorption by cells of the kidney
tubules etc.
L: Kidney tubules, glands
and their ducts etc. (kidney)
Simple Cuboidal Epithelium
S: Single layer of tall,
narrow cells
F: Movement of particles
out of the bronchioles of the lungs
by ciliated cells; partially responsible
for the movement of oocytes through
the uterine tubes by ciliated cells;
secretion by cells of the glands,
the stomach, and the intestines.
absorption by cells of the small
and large intestines
L: Glands and some ducts,
bronchioles of the lungs, auditory
tubes, uterus, uterine tubes,
stomach, intestines, gallbladder,
bile ducts, ventricles of the brain (Lining of
stomach and intestines)
Simple Columnar Epithelium
S: Multiple layers of cells that
are cube-shaped in the basal layer and
progressively flattened toward the surface
F: Protection against abrasion, a barrier against
infection, reduction of water loss from the body
L:
Keratinized— skin
nonkeratinized—mouth,
throat, larynx, esophagus, anus,
vagina, inferior urethra, cornea
Stratified Squamous Epithelium
the surface cells retain a nucleus and cytoplasm.
nonkeratinized
stratified squamous epithelium
the cytoplasm of cells at the surface is replaced
by a protein called keratin, and the cells
are dead
keratinized stratified epithelium
S: Multiple layers of
somewhat cube-shaped cells
F: Secretion, absorption,
protection against infection
L: Sweat gland ducts,
ovarian follicular cells, salivary
gland ducts
Stratified Cuboidal Epithelium
S: Multiple layers of cells
with tall, thin cells resting on layers
of more cube-shaped cells
F: Protection, secretion
L: Mammary gland ducts,
larynx, a portion of the male urethra
Stratified Columnar Epithelium
S: Single layer of cells;
some cells are tall and thin and
reach the free surface, and others
do not
F: Synthesize and secrete
mucus onto the free surface;
move mucus (or fluid) that
contains foreign particles over the
surface of the free surface and
from passages
L: Lining of the nasal
cavity, nasal sinuses, auditory
tubes, pharynx, trachea, bronchi
of the lungs
Pseudostratified Columnar Epithelium
S: Stratified cells that
appear cube-shaped when the
organ or tube is not stretched and
squamous when the organ or tube
is stretched by fluid
F: Accommodate
fluctuations in the volume of fluid
in organs or tubes; protect against
the caustic effects of urine
L: : Lining of the urinary
bladder, ureters, superior urethra
Transitional Epithelium
specialized columnar epithelial cells that are responsible for synthesizing and secreting mucus
goblet cells
are extensions of the cell that greatly increase free surface area. They occur in cells that absorb or secrete, such as serous membranes and the lining of the small intestine
Microvilli
are a specialized, elongated form of microvilli found in sensory structures, such as the inner ear
Stereocilia
consist of adhesive
glycoproteins that bind cells together and intracellular proteins
attached to intermediate filaments that extend into the cytoplasm
of the cells
desmosomes
similar to one-half of a desmosome, attach epithelial cells to the basement
membrane.
Hemidesmosomes
hold cells together and form a permeability
barrier
Tight junctions
formed by proteins in the
plasma membranes of adjacent cells that join one another to make
a very tight seal
Tight junctions
in glycoproteins, found just below the
tight junction
adhesion belt
a small, specialized contact region
between cells containing protein channels that aid intercellular communication by allowing ions and small molecules to pass from one cell to another
gap junction
contain both gap junctions and desmosomes that help hold adjacent cells in close contact.
intercalated disks
composed primarily of epithelium, with a supporting network of connective tissue
Glands
Glands with ducts are
called
exocrine glands (Both the glands and their
ducts are lined with epithelium)
some glands become
separated from the epithelium of their origin and have no ducts; these are called
endocrine glands (have extensive blood vessels)
cellular products of endocrine
glands
hormones
glands that are composed of many cells
multicellular glands
glands that are composed of a single cell
unicellular glands
glands that have a single, nonbranched duct
Simple glands
if there are multiple secretory regions that branch off the duct, then the gland is called
branched
have multiple, branched ducts
Compound glands
Glands with secretory regions
shaped as tubules
tubular
shaped in saclike structures
acinar or alveolar
most common type of secretion
merocrine secretion
involves the release of secretory products by exocytosis
merocrine secretion
involves the release of secretory products as pinched off fragments of the gland cells
Apocrine secretion
involves the shedding of entire cells
Holocrine secretion
a diverse primary tissue type that makes up
part of every organ in the body.
Connective tissue
differs from the other three tissue types in that it consists of cells separated from each other by abundant extracellular matrix.
Connective tissue
Functions of Connective Tissue (7)
- Enclosing and separating other tissues.
- Connecting tissues to one another.
- Supporting and moving parts of the body.
- Storing compounds.
- Cushioning and insulating.
- Transporting.
- Protecting.
extracellular matrix is produced by?
specialized cells of the various connective tissues
blasts
create the matrix
cytes
maintain
clasts
break it down for remodeling
cells that form fibrous connective tissue
Fibroblasts
maintain fibrous connective tissue
fibrocytes
form cartilage
Chondroblasts
maintain cartilage
chondrocytes
also called adipose cells, contain large amounts of lipid.
Adipocytes
play important roles in inflammation
Mast cells
continuously move from blood vessels into connective tissues.
White blood cells, or leukocytes
are large, phagocytic cells found in some connective tissue types. They are derived from monocytes, a type of
white blood cell.
Macrophages