Chapter 4- Pain Medications Flashcards

1
Q

salicylates do what?

A

Relieve pain by inhibiting synthesis of protaglandin

Reduce fever by stimulating the hypothalamus-producing dilation of peripheral blood vessels, ^ sweating

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2
Q

This drug inhibits platelet aggregation (anti-clotting)

A

Aspirin

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3
Q

If someone is having a heart attack, you should do what?

A

Give them a regular aspirin (non coated) sublingually

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4
Q

Adverse reactions of salicylates include:

A
  • Gastric distress
  • N/V
  • Bleeding
  • Hearing loss, tinnitus (ringing/buzzing in ears)
  • Reye’s syndrome (w/ children experiencing chickenpox or flu-like symptoms)
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5
Q

NSAIDS do what?

A
  • decrease inflammation

- reduce pain

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6
Q

How do NSAIDS work?

A

blockage of isoenzymes (cyclooxygenase) that convert arachidonic acids into prostaglandin

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7
Q

Opioids agonists work by?

A
  • reduce pain by binding to opiate receptor sites in the peripheral nervous system and the CNS
  • mimick the effects of endorphins, producing analgesia (inability to feel pain) and cough suppression
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8
Q

Opioid agonists treat what?

A
  • Pain relief in acute, chronic or terminal illness
  • control diarrhea
  • suppress coughing
  • induction and maintenance of general anesthesia
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9
Q

If a person wanted to take a salicylate without irritating their stomach that should take what?

A

A coated aspirin that won’t be absorbed as quickly as non-coated

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10
Q

Everybody taking a narcotic under our care is a what?

A

Falls risk

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11
Q

We should take extra precaution when using narcotics in what kind of patient?

A

Elderly

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12
Q

this does wasfwioeaft

A

1) prevent leakage of plasma from capillaries
2) suppress migration of PMN leukocytes
3) disrupt histamine synthesis
4) decrease antibody formation
5) decrease antibody formation
6) suppress release of hydrolytic enzymes

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13
Q

Aspirin also does this…

A

Inhibits platelet aggregation

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14
Q

What do we give children instead of aspirin for flu-like symptoms & chickenpox?

A

Tylenol

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15
Q

No more than ____ mg of acetaminophen in a day

A

3500 mg

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16
Q

Non-selective NSAID’s include?

A

ibuprofen, indomethacin (IV version of NSAID), ketorolac

17
Q

Selective NSAID’s include?

A

celecoxib

18
Q

These reduce the effects of NSAID’s

A

anti-coagulants

19
Q

A drug that is used to treat urinary tract infection symptoms (local anesthetic effect) and uses axo dye

A

Phenazopyridine (DRINK LOTS OF WATER WITH)

20
Q

Two major adverse reactions of opioid agonists include what?

A

Respiratory depression, orthostatic hypotension

21
Q

How do we access if a mother who just gave birth was taking drugs during her pregnancy?

A

Check babies poop

22
Q

Mixed opioid agonist-antagonist’s do what?

A

Relieve pain while reducing toxic effects and dependency

23
Q

Examples of opioid agonist-antagonist include?

A

Buprenorphine, nalbuphine (Nubain)-during birth

24
Q

DO not mix opioids with what because it could lead to death?

A

Respiratory & CNS depressants

25
Q

An example of an opioid antagonist would be what?

A

Naloxone- NARCAN&raquo_space; used for opioid overdose or drug abuse