Chapter 13- Anti-inflammatory, antiallergy & immunosuppressants

Question 1

Antihistamines do what?

Answer 1

Block the effects of histamine on target tissues

Question 2

Corticosteroids do what?

Answer 2

suppress the immune response

Question 3

Immunosuppressants do what?

Answer 3

reduce transplant rejection & treat autoimmune diseases

Question 4

What do histamine-1 receptor antagonists tx?

Answer 4

Type 1 hypersensitivity reactions (
nausea & vomiting control
Parkinson’s disease
Cushing’s disease, serotonin-associated diarrhea, cluster headaches & anorexia nervosa

Question 5

Corticosteroids: Glucocorticoids include which drugs?

Answer 5

Cortisone, Prednisolone, Prednisone

Question 6

What do glucocorticoids treat?

Answer 6

Suppress hypersensitivity and immune responses
Adrenocortical insufficiency
Immunosuppression
Inflammation

Question 7

Uricosurics treat what?

Answer 7

Chronic gouty arthritis

Tophaceous gout

Question 8

How do uricosurics work?

Probenecid

Answer 8

reduce reabsorption of uric acid

Question 9

Some antigout drugs include…

Answer 9

Allopurinol, Colchicine

Question 10

How does Allopurinol work?

Colchicine?

Answer 10

Allopurinol-inhibits xanthine oxidase (enzyme)

Colchicine-Reduces inflammatory response to urate crystals

Question 11

What do these drugs treat?

Allopurinol, Colchicine

Answer 11

Allopurinol-Gout

Colchicine-Acute gouty arthritis