chapter 4

Question 1

what uses macromolecules (proteins, polysaccharides, lipids, nucleic acids), small chemicals as a form of antigen recognition

Answer 1

b cell receptor (antibody, Ig)

Question 2

what uses mainly peptides displayed by MHC molecules on APCs as a form of antigen recognition

Answer 2

t cell receptor (TCR)

Question 3

what uses variable (V) regions of heavy and light chains of membrane Ig to mediate antigen recognition

Answer 3

b cell receptor (antibody, Ig)

Question 4

what uses variable (V) regions of a and b chains of the TCR to mediate antigen recognition

Answer 4

t cell receptor (TCR)

Question 5

what are the two isotype of antibodies that function with niave B cell antigen receptors

Answer 5

IgD and IgM

Question 6

when dealing with B cell receptors for antigens, when switching from IgM and IgD to other isotypes of antibodies, what regions dont change?
this means heavy chain in constant region is the one changing

Answer 6

variable regions dont change

Question 7

with this, the antigen binding is made up of 3 CDRs in Va and 3 CDRs in Vb

Answer 7

t cell receptor (TCR)

Question 7

with this, the antigen binding is made up of 3 CDRs in VH and 3 CDRs in VL

Answer 7

Ig (immunoglobulin)

Question 7

what chain occurs first from maturing from Pro-B to Pre-B in the steps of the maturation and selection of B lymphocytes

Answer 7

heavy chain occurs first

Question 8

what are the two positive selections in the steps of the maturation and selection of MHC-restricted T lymphocytes

Answer 8

weak recognition of class II MHC + peptide
and
weak recognition of class I MHC + peptide