bacteria 8 Flashcards
preference of bacteria for particular locations in the body
- surface colonization
______ on bacterium
______ on host cells
adhesins on bacterium and receptors on host cells
in this bacteria for surface colonization,
1. bacterial proteins on tips of pili interact with glycolipids/glycoproteins on host epithelial cells
- bacterial proteins at the cell surface interact with their own translocated intimin receptor (TIR)=
(for E.COLI bacteria!!)
gram-negative bacteria
intimins
in this bacteria for surface colonization,
it often binds host fibronectin which binds integrins
gram positive (staphyloccus)
give example of molecule on human cell that is recognized and bound by SRRP for gram positive bacteria for surface colonization
sialic acid
what is a mechanism that pathogenic bacteria use to envade host immune system defenses?
addition of sialic acid to LPS
gram negative bacteria often bind to host cells by
bacterial fimbriae proteins interacting with host cell glycolipids
what blocks access of the membrane attack complex to the bacterial plasma membrane
function of LPS on bacterial cells
this cleaves the complement component into inactive fragments
C3b peptidase
*****what is the effect of collagenases when they are toxins encoded by pathogenic bacteria
they degrade collagen and allow bacteria to enter host cell or penetrate host tissues