Chapter 31 Flashcards
What is the difference between the chemically (rarely used) drug name, the generic (official) drug name, and the trade/brand/proprietary (trademarked) drug name?
- chemically: exact description of medication’s composition and molecular structure
- generic: assigned by the drug manufacturer
- trade/brand/proprietary: name under which manufacturer markets the medication; easy to pronounce, spell, and remember
What is the most common form of medication? What are the 3 forms this can come in?
– oral (PO)
- solid
- liquid
- others – lozenges, aerosols, etc.
What are the 4 types of PO medications that cannot be crushed?
- capsules
- enteric-coated
- sublingual
- extended-release
What is absorption in relation to medication?
how fast medications are absorbed into the bloodstream
What are the 4 factors that influence absorption rate?
- route of administration
- blood flow to site of administration
- body surface area
- lipid solubility
What are the 3 fastest routes of absorption?
- IV – fastest
- IM
- subq
Where does metabolism of medication usually occur within the body?
liver
metabolized into a less potent/inactive form
What are the 5 organs that participate in excretion of medication from the body?
- kidneys
- impaired kidney function increases risk for toxicity
- liver
- bowels
- lungs
- exocrine glands
What is the difference between the therapeutic effect and the adverse effect of medication?
- therapeutic effect: expected/predicted physiological response; what you want to happen
- adverse effect: unintended/undesirable/unpredicted response; what you don’t want to happen
What is the difference between side effect, toxic effect, and idiosyncratic reaction to medication?
- side effect: predictable but unavoidable secondary effect
- toxic effect: accumulation of medication in the bloodstream
- idiosyncratic reaction: unpredictable overreaction, underreaction, or different reaction from normal response to medication
What does it mean when medication is said to be synergistic?
one medication modifies the action of another medication
What does it mean to have increased medication tolerance?
more medication is required to achieve the same therapeutic effect
What is the therapeutic range of a medication?
lowest and highest amounts of medication to achieve therapeutic effect
What is the difference between sublingual and buccal medication administration?
- sublingual – placed under the tongue to dissolve
- buccal – placed against mucous membranes of the cheek
How many deaths/year do medical errors result in?
250,000