Chapter 3: Extensions to Mendel’s Laws Learning Objectives Flashcards
o Conclude from the results of crosses whether a single gene or multiple genes control a trait
F2 phenotypic ratio for dihybrid crosses = 9:3:3:1
o Infer from the results of crosses the existence of interactions between alleles of different genes including: complementation, epistasis, and redundancy
F2 Phenotypic Ratios: • Complementary: 9:7 • Recessive Epistasis: 9:3:4 • Dominant Epistasis 1: 12:3:1 • Dominant Epistasis II: 13:3 • Redundancy: 15:1
o Predict from the results of crosses whether a gene is polymorphic or monomorphic in a population
Depends on dominance relations for each affected trait
o Explain how continuous traits, like human height and skin color, are controlled by multiple alleles of multiple genes
Continuous trait: gene interaction with each other and environment produces phenotypic variation
A continuous trait can have any value of expressions between two extremes because of a combination of genetics and environment
o Recognize when a given phenotype is different individuals does not correspond to the same phenotype
In incomplete penetrance, a phenotype is expressed in fewer than 100% of individuals having same genotype
In variable expressivity, a phenotype is expressed at different levels among individuals with same genotype
o Categorize allele interactions as completely dominant, incompletely dominant, or codominant
Complete: hybrids resemble one of two pure-breeding parents
Incomplete: hybrid resembles neither parent; phenotype is intermediate between both parents
Codominant: hybrid shows trait from both pure-breeding parents
o Recognize progeny ratios that imply the existence of recessive lethal alleles
2:1 ratio indicates recessive lethal (instead of 3:1)