Chapter 16.1: Overview of Eukaryotic Gene Regulation Flashcards
1
Q
What is a similarity between eukaryotic and prokaryotic gene regulation?
A
o In both, transcriptional regulation occurs through the attachment of DNA-binding proteins to specific DNA sequences that are in the vicinity of the transcription unit itself
2
Q
Why does controlling expression in eukaryotes require additional levels of complexity? (4)
A
o Chromatin structure often makes DNA unavailable to the transcription machinery
o Additional RNA processing events occur
o Transcription occurs in the nucleus, but translation takes place in the cytoplasm
o Gene regulation needs to control cellular differentiation into hundreds of specialized cell types