Chapter 27: The Hepatoportal System Flashcards
an abnormal connection between the hepatic artery and the portal venous system
arterioportal fistula
an abnormal connection between the hepatic artery and the hepatic vein
arteriosystemic fistula
an abnormal accumulation of fluid within the peritoneal cavity. It is the most common complication of cirrhosis
ascites
any nonmalignant venous thrombosis. This term is most often used in the context of malignancy, to differentiate malignant from nonmalignant thrombus
bland thrombus
hepatic venous outflow obstruction at any level from the small hepatic veins to the junction of the IVC and the right atrium, regardless of the cause of obstruction
Budd-Chiari syndrome
A chronic diffuse degenerative disease in which normal liver cells are damaged and replaced by fibrous connective tissue and regenerating nodules
cirrhosis
spiraling, swirling, “helix” flow pattern demonstrating hepatopetal, hepatofugal, or simultaneous bidirectional flow; uncommon flow pattern seen in 2% of the population
Helical portal vein flow
Compensatory mechanism to maintain perfusion to the liver by arterial vasodilation when portal vein flow is obstructed in patients with advanced cirrhosis
hepatic arterial buffer response
a pleural effusion in patients with liver cirrhosis in the absence of cardiopulmonary disease. The pathophysiology involves the passage of ascitic fluid from the peritoneal cavity to the pleural space through diaphragmatic defects
hepatic hydrothorax
Refers to retrograde flow, away from the liver (physiologically abnormal direction of flow within portal-splenic venous system)
hepatofugal
Refers to antegrade flow; toward the liver (pathophysiologically normal direction of flow within the portal-splenic venous system)
hepatopetal
Elevated pressure gradient between the portal vein and IVC or hepatic veins of 10 to 12 mm Hg or greater
portal hypertension
formation of abnormal blood vessels that shunt portal blood flow bypassing the liver to the systemic circulation, decompressing increased portal venous pressure
portosystemic collaterals
formerly known as hepatic veno-occlusive disease; is a syndrome of tender hepatomegaly, RUQ pain, jaundice, and ascites; most often occurring in patients in patients undergoing hematopoeitic cell transplantation, and less commonly following radiation therapy to the liver, liver transplantation, and ingestion of alkaloid toxins
sinusoidal obstruction syndrome (SOS)
a percutaneously created connection within the liver between the hepatic vein and the portal vein that allows blood flow to bypass the liver as a means to reduce portal pressure in patients with complications related to portal hypertension
transjugular intrahepatic portosystemic shunt (TIPS)
Indications for hepatoportal duplex ultrasound
liver cirrhosis
portal hypertension
thrombus
Budd-Chiari syndrome
Pre/post interventional procedures
abdominal trauma
sudden onset of ascites
patients with a history of abdominal malignancy
most often joins the portal system at the splenoportal confluence; with portal hypertension, diameter <7mm; can demonstrate hepatofugal flow that often leads to esophageal varices
coronary vein (left gastric vein)
origin, gastroesophageal junction, lower esophagus, and submucosal region of the gastric fundus; dilated vessels posterior to the left lobe of the liver at the GEJ
gastroesophageal veins
fetal remnant arising from LPV, coursing along the anterior edge of the falciform ligament to the abdominal wall; connects to systemic veins around the umbilicus “caput medusa”; located in the fissure for the ligamentum teres; diameter >3mm, hepatofugal flow
recanalized paraumbilical vein/abdominal wall
large tortuous vessels seen in the hilar region of the spleen and left kidney; shunts blood to the left renal vein, terminating in the IVC, decompressing the portal circulation
splenorenal veins
portosystemic shunt between the cystic vein and the right branch of the portal vein, systemic veins of the anterior abdominal wall, or patent portal vein branches within the liver; dilated pericholecystic vascular channels, 3-8 mm in diameter within or outside the gallbladder wall, demonstrating low-velocity continuous flow
gallbladder varices
most common imaging technique used to evaluate the liver and its vasculature
duplex sonography
The hepatic artery supplies approximately ____ of blood to the liver
25%
carries oxygenated blood through branches in portal triad and enters sinusoids to reach central veins within liver
hepatic artery
The portal vein supplies approximately ____ of blood to the liver
75%
carries nutrient rich blood from the gastrointestinal tract to the portal triad and enters sinusoids to reach central veins
portal vein
Dual blood supply liver
hepatic artery
portal vein
actual beginnings of hepatic venous systems; enter sublobular veins, which unite and converge to form 3 hepatic veins that drain into IVC
central veins
The ______ comprise primary hepatic outflow vessels.
hepatic veins
The portal triad consists of:
branch of hepatic artery
branch of portal vein
bile duct
begins at junction of splenic vein and superior mesenteric vein
main portal vein
runs along lesser curvature of stomach; drains into portal system near portal splenic confluence
main portal vein
The main portal vein lies ____ to the IVC>
anterior
transverse fissure on visceral surface of liver between caudate and quadrate lobes
porta hepatis
At the porta hepatis, the _____ and _____ enter the liver and the _____ leaves the liver.
portal vein
hepatic artery
hepatic duct
The main portal vein divides into a smaller, more anterior and cranial _____ portal vein and a larger, more posterior and caudal ____ portal vein.
left
right
The portal veins branch into ____ and ____ divisions on the left.
medial
lateral
The portal veins branch into ____ and _____ divisions on the right.
anterior
posterior
The _____ have no valves.
portal veins
composed mostly of loosely arrayed, non parallel connective tissue fibers and minor amount of collagen
main portal vein
composed mostly of tightly packed collagen fibers
hepatic veins
The hepatic veins are ______.
intersegmental
Patient preparation
fast overnight
The _____ branches off the celiac trunk to the right.
hepatic artery
excellent visualization of porta hepatis
right coronal oblique
provides optimal visualization of splenic vein and splenic artery
left coronal oblique
The liver is evaluated for ____, ___, and ____.
size
texture
surface contour
The normal portal vein diameter during quiet respiration is ___ mm or less.
13
The portal vein may increase up to __ mm with deep inspiration
16
Normal portal venous outfloq
hepatopetal; laminar, low-velocity flow with mild respiratory and moderate pulsatile variations
abnormalities associated with helical flow
portosystemic collaterals
Portal vein velocity ____ during inspiration and _____ during expiration
decreases
increases
Postprandially, portal vein flow velocity increases __-___%
50-100
Resting PSV in portal vein
16 cm/s
mean flow velocity portal vein
19.6 + 2.6 cm/s
Diameter of the splenic vein measures up to __ mm.
10
Normal splenic vein flow and direction
antegrade
Splenic vein velocity _____ during inspiration and _____ during expiration
decreases
increases
Normal PSV of splenic vein
9-30 cm/s
Normal mean velocity of splenic vein
5 to 12 cm/s
Normal spectral Doppler waveform of splenic vein
respirophasic with slight pulsatility
drains into portal system near portal splenic confluence
left gastric or coronary vein
The left gastric vein measures up to __ mm in diameter
6
The superior mesenteric vein can measure up to __ mm at the trunk.
10
Normal flow of SMV
antegrade
Normal PSV of SMV
8 and 40 cm/s
Normal mean velocity of SMV
9 to 18 cm/s
Normal spectral Doppler waveform of SMV
respirophasic with slight pulsatility
SMV velocity ____ during inspiration and ____ during expiration
decreases
increases
Postprandial velocity SMV increases __ - ___ %
50-100
Normal diameter of right hepatic vein
less than 6 mm
The hepatic veins normally exhibit pulsatile waveforms with two ____ waves and two ____ waves.
antegrade
retrograde
Ventricular systole demonstrates the __-wave
S