Chapter 26: HIV

Question 1

Singe Pill Regimens

Answer 1

Biktarvy
Triumeq
Dovato

Question 2

Biktarvy

Answer 2

Bictegravir
Emtricitabine
Tenofovir alafenamide

Question 3

Triumeq

Answer 3

Dolutegravir
Abacavir
Lamivudine

Question 4

Dovato

Answer 4

Dolutegravir

Lamivudine

Question 5

HIV Life Cycle

Answer 5

Question 6

Drugs That Work In Stage 1

Answer 6

Stage 1: Binding and Attachment
CCR5 antagonist: maraviroc
Attachment inhibitor: Fostemavir
Post-attachment Inhibitor: Ibalizumab-uiyk

Question 7

Drugs That Work In Stage 2

Answer 7

Stage 2: Fusion

Fusion Inhibitor: Enfuvirtide

Question 8

Drugs That Work In Stage 3

Answer 8

Stage 3: Reverse Transcription
Nucleoside reverse transcriptase inhibitors (NRTIs)
Non-nucleoside reverse transcriptase inhibitors (NNRTIs)

Question 9

Drugs That Work In Stage 4

Answer 9

Stage 4: Integration

Integrase strand inhibitors (INSTIs)

Question 10

Drugs That Work In Stage 5

Answer 10

Stage 5: Replication

None

Question 11

Drugs That Work In Stage 6

Answer 11

Stage 6: Assembly

None

Question 12

Drugs That Work In Stage 7

Answer 12

Stage 7: Budding and Maturation

Protease Inhibitors

Question 13

NRTI Backbone

Answer 13

Descovy (emtricitabine/tenofovir alafenamide)
Truvada (emtricitabine/tenofovir disoproxil)
Make up the NRTI backbone in most regimens

Question 14

Two Pills Once Daily: Tivicay + Truvada

Answer 14

Dolutegravir

Emtricitabine/TDF

Question 15

Two Pills Once Daily: Tivicay + Descovy

Answer 15

Dolutegravir

Emtricitabine/TAF

Question 16

Two Pills Once Daily: Isentress + Truvada

Answer 16

Raltegravir

Emtricitabine/TDF

Question 17

Two Pills Once Daily:: Isentress + Descovy

Answer 17

Raltegravir

Emtricitabine/TAF