Chapter 2.6 Cell Division .... Flashcards
What’s mitosis ?
3
Type of nuclear division that produces daughter cells genetically identical to each other and to the parent cell .
What’s the order Of the cell cycle starting with M phase ?
1-M phase 2-G0 phase 3-G1 phase 4-Synthesis 5-G2
What happens in M phase ?
3
- cell growth
- PMAT
- Cytokinesis
What happens in G0 phase ?
3
Apoptosis
Differentiation
Senscene
What happens in G1?
4
- cells growth
- Organelles DUPLICATE
- Biosynthesis
- P53 suppressor ( Tumour suppressor)
What happens in synthesis phase ?
2
- DNA Replicates
- Identical sister chromatids
What happens in G2 ?
1
GROWTH
What are the checkpoints ?
3
1- Metaphase checkpoint
2-G1 checkpoint
3- G2 checkpoint
What’s the purpose of the checkpoints?
4
- Prevent uncontrollable division (cancer )
- Detect / repair damage
- ensure cell cycle isn’t reversed
- ensure DNA is duplicate ONCE
What does metaphase checkpoint do ?
1
- cell checks that all chromosomes are attached to spindle before mitosis can continue !
Why do we need mitosis ?
3
- growth
- tissue repair
- Asexual reproduction ( amoeba , paramecium )
What happens in interphase ( mitosis )
3
- cell prepares for cell division
1-organelles divide
2-DNA unravels
3-ATP Content rises
What happens in Prophase ( mitosis ) ?
4
- chromosomes shorten and thicken
- Nuclear envelope breaks down
- Centriole divides and moves to opposite end of cells
- Cytoskeleton TUBULIN threads form
What happens metaphase ( mitosis ) ?
3
- chromosomes line up
- chromatids attach to spindle
- attached by centromeres
What happens in anaphase ?
Chromatids ?
3
1- centromere divides
2-sister chromatically pulled apart by motor protein
What happens telophase ?
3
1-separated chromosomes reach opposite poles
2-new nuclear envelope forms
3-cell contains 2 NUCLEI GENETICALLY IDENTICAL TO EACHOTHER