Chapter 24 (Part 2) Flashcards
Viruses are not considered ‘living’ because
hey possess only a few properties of living organisms.
Viruses do not have..
a cell membrane or cellular organelles and they can not replicate outside of host cells
viruses hereditary material can be…
DNA or RNA
viruses can only infect specific cell types that contain…
receptors that the virus can bind to
zoonotic infections
Viruses can sometimes bind to similar receptors in more than
one species
Viruses that infect multiple organisms have a higher rate of
mutation, therefore a higher rate of
‘evolution’
pandemic
an infectious disease epidemic that has spread across a large region: ie. multiple continents or worldwide.
Viruses are how many times smaller than human cells?
100 to 10000 times smaller
Helical viruses
have a hollow centre and can be very long
Polyhedral viruses
have only protein surrounding them
Enveloped viruses
steal membrane from the host to help them bind to new cells
Bacteriophages
only infect bacteria, complex structure, inject genetic material into a bacterium (the remainder is discarded.
lytic cycle
If a virus kills the infected host
lysogenic cycle
If the virus integrates itself into the host genome and remains dormant as the host cell replicates
Attachment
Proteins on the virus capsid bind to a specific receptor
Infiltration
The host cell takes up the virus
Replication
The virus uses host cell organelles, nutrients, and ATP to make new virus particles
Assembly
New virus particles form and are released from the host cell, causing lysis and death of the host cell
viruses that contain RNA must do what before they replicate within the host cell?
convert RNA to DNA
The process of converting RNA to DNA requires the enzyme…
reverse transcriptase
Why do RNA viruses mutate more rapidly?
reverse transcriptase enzymes make many mistakes during replication and lack “proofreading” ability
This high mutation → new variants
HIV
is an RNA virus that infects specific white blood cells and integrates into the host cell’s genome: (a retrovirus)
Since most of these immune cells die by lysis…
Leads to low levels of properly functioning immune cells
Decline in immune cell numbers …
Body becomes more susceptible to opportunistic infections