Chapter 23 Respiratory System Flashcards
Five functions of the respiratory system
Pulmonary ventilation
Provides large surface area for gas exchange
Protections secretions
Phonation
Sensations olfaction
Structures of the upper respiratory system
External naris
Nasal cavity
Internal naris
Pharynx (nasopharnyx, oropharnyx, laryngealpharnyx)
Structures of the lower respiratory tract
Trachea
Primary bronchi
Secondary bronchi
Tertiary bronchi
Bronchioles
Terminal bronchioles
Respiratory bronchioles
Alveolar duct
Alveoli
The respiratory mucosa of the majority of the tract, from the trachea down to the terminal bronchioles, is lined with
Pseudo stratified ciliated columnar epithelium
In the ______ the lamina propia contains numerous mucus glands.
Upper respiratory tract
In the _______ the lamina propia contains smooth muscle from the trachea to the terminal bronchioles
Lower respiratory tract
What is the mucus escalator
Any debris that mucus pushes out of the respiratory tract
Requires secretion of mucus
Membrane of the aveoli has ?
Simple squamous epithelium
What is the function and epithelial lining of the nasopharnyx
Moves air and has pseudo stratified ciliated columnar epithelium
What is the function and epithelial lining of the oropharnyx
Moves air and food
Has stratified squamous epithelium
What is the function and epithelial lining of larnygopharnyx
It moves air and food
Lining is pseudo stratified ciliated columnar epithelium
What is the function and epithelial lining of the trachea
It moves air
The lining is pseudo stratified ciliated columnar epithelium
Low oxygen
Hypoxia
Without oxygen
Anoxia
Hole in the wall of chest cavity
Pneumothorax
Collapsed lung
Atelactasis
True breathing quiet respiration
Eupnea
Not breathing, temporary stoppage of breathing
Apnea
Forced exhalation and rapid breathing rate (sympathetic activation)
Hypernea
Ability of an organ to change shape to accommodate changes in volume
Compliance
Movement of gases to and from the gas exchange surface
(From the atmosphere to aveoli and back out)
Pulmonary ventilation
Exchange of gases between the atmosphere and our blood
External respiration
Exchange of gases between the blood and tissues (interstitial fluid)
Internal respiration
The pressure of a gas in a closed system is inversely proportional to the volume of the system
Boyles law
For ______ the volume of the lungs increases, decreasing the pressure of the air in the lungs below atmospheric pressure.
Inhalation
Inhalation involves contraction of the ?
Diaphragm
External intercostals
Which increase volume of the thorax
For _____ the volume of the lungs decreases due to ______, the pressure of the gas in the lungs will increase above atmospheric pressure and force the gases out of the lungs
Exhalation
While in _______, exhalation does not involve any muscle contraction
Eupnea or quiet breathing
During forced exhalation or hypernea the _______ contract to decrease the volume of the thoracic cavity even further to for even more air out
Internal intercostals and rectus abdominus contract
Intrapleural pressure is always lower than intrapulmonic pressure
If the pressure was higher than the lungs would collapse
What would happen if the intraplueral pressure were greater than intrapulmoinc pressure? What condition would cause this ?
Pneumothorax
This requires o2 to move from the atmosphere, across the alveoli, into the blood. It also requires CO2 to move out of the blood, across the alveoli, and into the atmosphere. This results in the conversion of deoxygenated blood into oxygenated blood.
External respiration
Each gas in a system will exert its own pressure as if all other gases were not present
Dalton’s law
It results in the conversion of oxygenated blood into deoxygenated blood
Internal respiration
The tissue lining initially in the nasal cavity
Stratified squamous epithelium
It involves inhalation and exhalation. It does not involve any gases crossing the exchange surface and entering or leaving the blood stream
Pulmonary ventilation
Basically, as volume increases, pressure decreases and vice versa. P and V have an inverse relationship. This means if one increases, the other must decrease.
Boyles law
Is on the wall of the thoracic cavity
Parietal pleura
Is on the organs
Visceral pleura
Atmospheric pressure @ sea level is
760 mmHG
During inhalation ______ will increase and _____ will decrease
Volume
Pressure
External intercostals contract during
Inhalation/quiet respiration
During _____ pressure will increase and volume will decrease
Exhalation
Exhalation is active in
Hypernea
As muscles relax, volume increases and pressure decrease inhale extra o2
Internal intercostals contract and ABS contract
Hypernea active respiration
Is the fluid like substance that coats inside of alveoli helps keep open, provides surface tension, Prevents lungs from collapsing on itself.
Surfactant
The pressure of each gas is called partial pressure.
The total pressure of the system is sum of all partial pressures of all gases in the system.
Basically, each gas in a system behaves as if it is the only gas in the system.
Dalton’s law of partial pressures
Pressure outside the lung between the pleural membranes
Intraplueral pressure
This requires o2 to move from the blood, across the capillary wall, and into IF or tissue. It also requires co2 to move out of the IF or tissue, across the capillary wall, and into the blood.
Internal respiration
Made up of 4 protein subunits 2 alpha and 2 beta
Contains a molecule of heme that contains iron that carry one molecule of O2
Hemoglobin
Is a pigment that appears deep red when bound to o2, and a deep blue when bound to co2
Heme
Carbon dioxide is transported in 3 ways
7% is transported in dissolved plasma
23% is transported to hemoglobin as carbaminohemoglobin
70% transported in plasma as bicarbonate ions
Formation of bicarbonate ions
- CO2 enters and RBC and an enzyme called carbonic anhydrase causes co2 and h2o to combine and form carbonic acid
- Carbonic acid dissociates H+ and HCO3. Hydrogen binds to Hb and is carried by it.
- A counter current exchange pump, pumps the bicarbonate ion out of the RBC into the plasma and pumps chloride ion into RBC. This process is called chloride shift.
The basic respiratory rhythm is controlled by the respiratory center which is made up of autonomic centers in the
Medulla and pons
Is in the medulla and is made up of two sub centers
Respiratory rhythmic center
Respiratory rhythmic center is made up of two sub centers
Dorsal respiratory group
Ventral respiratory group
An inspiratory center that stimulates the diaphragm and external intercostals to contract and cause inspiration
Dorsal respiratory group
An expiratory center that is active only during forced exhalation
Ventral respiratory group
The _____ functions during every cycle and sends axons through the phrenic nerve
DRG
When active, the _____ stimulates the internal intercostals and rectus abdominus muscles to contract
VRG
Is located in the pons and stimulates the DRG to cause inhalation
Apneustic center
Is located in the pons and inhibits the DRG so that quiet exhalation occurs
Pneunotaxic center
Mechanoreceptors respond to changes in volume and pressure during forced or active respiration Hypernea
Inflation reflex
Deflation reflex
Prevents over-expansion of the lungs. As the volume of the lungs increases during extended inhalations Mechanoreceptors in the lungs and thoracic muscles send action potentials to inhibit the DRG stop inhalation and stimulate VRG begin exhalation
Inflation reflex
Prevents the lungs from collapsing due to over deflation. As the volume of the lungs decrease Mechanoreceptors will send action potentials to inhibit the VRG stop exhalation and stimulate the DRG begin inhalation
Deflation reflex
Involve coughing and sneezing which are responses to injury or irritation of the respiratory mucosae by pathogens and debris.
Protective reflexes
The gas exchange surface is ?
The aveoli
A bunch of alveolar sacs represent a
Lobule
Several lobules make a
Lobe
Several lobes will make a ?
Lung
External intercostals contract
Diaphragm contracts
Inhalation active
Exhalation passive
Quiet respiration Eupnea
Inter intercostals abdominal muscles contract
Inhale extra o2
Exhale active
Hypernea active respiration
Active respiration Hypernea is under ?
Sympathetic control
Pressure inside of the lungs
Intrapulmonic pressure
No air is moving in or out
Intrapulmonic pressure
The ability of a gas to dissolve in a solution
Solubility
Oxygen is transported in two ways
3% transported in plasma
97% transported by hemoglobin
Stimulates DRG
No more DRG
Apnuestic center
Pneumotaxic center
Pons
DRG and VRG are both located in the ?
Medulla
The apnuestic and pneumotaxic center are located where ?
Pons