Chapter 18 Flashcards
Maintenance of a constant and optimal internal environment
Homeostasis
A response to a stimulus that increases that stimulus
Ex. Labor contractions
Positive feedback
Is response to a stimulus that decreases the stimulus
Negative feedback
Secretions onto the external surfaces of the body
Ex. Mucus, saliva, digestive secretions, sweat, reproductive secretions
Exocrine secretions
Secretions Into surrounding interstitial fluid or bloodstream
Endocrine secretions
Any detectable change in the environment
Stimulus
Any substance released by a group of cells that has a tropic effect on a distant group of cells
Hormone
Any cell that has a receptor for that specific hormone
Target cells
A hormone in response to a stimulus can release a hormone into the blood stream an can target multiple cells, in multiple locations in various parts of the body at great distances and will bind to those target cells, the cells will with the appropriate target cells and they will give the appropriate response
Endocrine communication
Transmission to the next cell/cell to cell/ rapid response/ rapid decay
Synaptic communication
Communicate to distant cells at multiple targets
Slow response/mins, hours,days,weeks, months
Response lasts a long time (long duration)
Endocrine communication
Integral membrane proteins to which a hormone will bind
Membrane receptor
second messenger “G protein” this will initiate a cascade of enzymes that eventually enter a nucleus and turn the gene off or on.
Transduction cascade
Hormone passes through the cell membrane and binds to a receptor inside the cytoplasm of the target cell
Intracellular receptor
All intracellular and intranuclear receptors have to be ?
Derivatives of lipids or cholesterol
All hormones that have membrane receptors are derived from
Amino acids or proteins (peptide polypeptide)
If the hormone binds to a membrane receptor the hormone is a
Protein (polypeptide) or amino acid (peptide) derivative
The posterior pituitary is also called the ________ of the pituitary gland.
Neurohypophysis or pars nervosa
The two hormones of the posterior pituitary are ?
ADH anti diuretic hormone
OTC oxytocin
These two hormones are produced in the special nuclei of the hypothalamus. The neurons of the hypothalamus extend their axons into the posterior pituitary and elevate their hormones into the blood stream. The hypothalamus can detect a stimulus and then releases a hormone to correct a problem.
ADH and oxytocin
The anterior pituitary is also called the ________ because it acts like a gland.
Adenohypophysis
It controls the release of several other known hormones and is therefore called the master control gland.
Anterior pituitary gland
In this pathway, the ______ is the detecting organ. It cannot synthesize the hormones that corrects a change in homeostasis.
Hypothalamus
Adenohypophysis
Neuroendocrine reflex
Complex endocrine reflex
Post pituitary gland
Anterior pituitary gland
Too much T3 T4
Too little T3 T4 or not producing enough TSH
Hyperthyroidism
Hypothyroidism
Involves hypothalamus and posterior pituitary
Neuroendocrine reflex
(Not in brain) Endocrine organ (somewhere in the body) detects a stimulus releases a hormone into bloodstream binds to a target cell and gives a response
Simple endocrine reflex
The endocrine organ is a group of cells of a particular nucleus in the hypothalamus that detects a stimulus they send axons through the infundibulum through the posterior pituitary, the cells release the hormone at the posterior pituitary it travels through the blood stream binds to target cells and elicit a response
Neuroendocrine reflex
Some stimulus detected in the hypothalamus by a group of cells, that group of cells is going to release a hormone, that hormone is going to travel through the infundbilium and pop out of the bloodstream at the anterior pituitary, that hormone is going to bind to a second group of cells. They will release a second hormone that binds to target cells to elicit a response.
Complex endocrine pathway
Vasopressin
Antidiuretic hormone
T3
T4
You need iodine to make this hormone
Triiodothyronine has 3 iodines
Tetraiodothyronine has 4 iodines
Remain functional much longer, because when these hormones enter the blood stream, more than 99% of them become attached to special transport proteins
Thyroid hormones and steroid hormones
Thyroid have small glands called thyroid follicles filled with
Colloid, inside of the colloid is filled with t3 t4
Sits between the apples apple and manubrium
Thyroid gland
Most hormones that target intracelluar receptors are
Steroid and thyroid hormones