Chapter 23: MNT for Ovarian CA

Question 1

What type of cells get cancer in ovarian CA? Which is the most common?

Answer 1

Epithelial cells - cover the ovary — the most common

Germ cells - inside the ovary

Stromal cells - produce female hormones

Question 2

What are the symptoms of advanced ovarian CA?

Answer 2

stomach/pelvic pain or pressure, early satiety, involuntary wt loss and abd swelling — 70% of cases (early symptoms often ignored)

Question 3

What is the 5-year survival rate for ovarian CA?

Answer 3

94% - stage IA
66% - stage II
34% - stage III
18% - stage IV

Question 4

What are the risk factors for ovarian CA?

Answer 4

Age - risk increases with age
HT and BMI - higher height and BMI > 30 increases risk
Reproductive Hx - giving birth, oral contraceptives for > 5 yrs, breastfeeding, and tubal ligation REDUCE risk
Family Hx - 5-15% are genetic
Genetic mutations - BRCA1, BRCA 2, RAD51C

Question 5

How many (%) of advanced cases of ovarian CA need intestinal surgery as well?

Answer 5

30-50%

Question 6

How many (%) of patients that receive pelvic radiation develop GI symptoms?

Answer 6

70% - usually diarrhea

Question 7

What % of ovarian CA patients experience Malignant Bowel Obstruction (MBO)?

Answer 7

20-50%