chapter 20 : Acid- Base Balance Flashcards
acid base balance = keeping the concentration of hydrogens ions in body fluids constant
all water solutions contain hydrogen ion (H+) and hydroxide (OH-)
a solution’s hydrogen ion concentration compared with hydroxide concentration
PH
PH 7.0 = neutral (water )
a PH higher than 7.0
(lower concentration of hydrogen than hydroxide ions)
alkaline
a PH lower than 7.0
(Higher hydrogen ion concentration than hydroxide ions)
(the higher the hydrogen ions concentration the lower the PH)
acid
gastric juices is the most acidic substance in the body (PH is 1.6)
saliva PH is 7.7 which is alkaline
blood PH is 7.35 - 7.45
(aterial and venous blood refer to the systemic circulation)
venous blood 7.37 (less alkaline)
aterial blood 7.45
the change of 1 ph unit represents a 10 fold difference in hydrogen ion
ph 7 - ph 6 is a 10 fold increase
ph 7 to ph 5 is a 100 fold increase
ph 5 to ph 7 is a 100 fold decrease
the body has 2 types of mechanisms regulating the ph of its fluids
- chemical ph control mechanism = based on buffers which acts immediately to prevent harmful swings in ph when an acid or base is added to it
- physiological ph control mechanism = reverse harmful ph shifts by respiration
chemical ph control mechanisms = use exchange reactions to lessen the effects of acids and bases on ph
physiologocial ph control mechanism = eliminating substances from the body or retaining substances in the body divided into ( respiratory/ urinray mechanisms)
the lungs remove more than 30ml of carbonic acid each day from the venous blood by elimination of carbon dioxide
The main blood buffer is sodium bicarbonate (NaHCO3) and carbonic acid (H2CO3)
NaHCO3 is the main buffer of the normally occurring “fixed” acids in the blood
lactic acid is one of the most abundant of the “fixed” acids (acids that do not break down to form gas)
H2CO3 is the most abundant acid in body fluids because it is formed by buffering fixed acids
ingesting large amounts of sodium bicarbonate (NaHCO3) to counteract the effects of lactic acid build up
bicarbonate loading
respiratory mechanisms relies on ventilation (breathing) to control ph in the body
every expiration, CO2 diffused out of the pulmonary blood as it moves through the lund capillaries ( if no CO2 leaves your body CO2 would increase)
urninary mechanism control depends on normal functions of the kidneys
kidneys are the most regulators of blood ph, they excrete excess base
more acids than bases are excreted by kidneys
diabetic ketoacidosis = causes the blood to become dangerously acidic
ketonuris = the excretion of abnormally large amounts of ketone bodies in the urine