Chapter 2 - Drug Taking Behavior: The Personal and Social Concerns Flashcards
Toxicity
The physical or psychological harm that a drug might present to the user.
Dose
The quantity of drug that is taken into the body, typically measured in terms of milligrams or micrograms.
Acute Toxicity
The physical or psychological harm a drug might present to the used immediately or soon after the drug is ingested into the body.
Dose-Response Curve
An S-shaped graph showing the increasing probability of a certain drug effect as the dose level rises.
Effective Dose (ED)
The minimal dose of a particular drug necessary to produce the intended drug effect in a given percentage of the population.
Lethal Dose (LD)
The minimal dose of a particular drug capable of producing death in a given percentage of the population.
Therapeutic Index
A measure of a drug’s relative safety for use, computed as the ratio of the lethal dose for 50% of the population to the effective dose for 50% of the population.
Margin of Safety
The ration of a lethal dose for 1% of the population to the effective dose for 99% of the population.
Drug Abuse Warning Network (DAWN)
A federal program in which metropolitan hospitals report the incidence of drug-related lethal and nonlethal emergencies.
Drug-Related ED Visit
An occasion on which a person visits and emergency department (ED) for a purpose that is related to a recent drug use.
Chronic Toxicity
The physical or psychological harm a drug might cause over a long period of use.
Tolerance
The capacity of a drug to produce a gradually diminished physical or psychological effect upon repeated administration of the drug at the same dose level.
Behavioral Tolerance
The process of drug tolerance that is linked to drug-taking behavior occurring consistently in the same surroundings or under the same circumstances. Also known as conditioned tolerance.
Physical Dependence
A model of drug dependence based on the idea that the drug abuser continues the drug-taking behavior to avoid the consequences of physical withdrawal symptoms.
Psychological Dependence
A model of drug dependence based on the idea that the drug abuser is motivated by a craving for the pleasurable effects of the drug.