Chapter 2 Flashcards

1
Q

Muscle strength is determined by?

A
  1. Cross sectional area

2. Coordinated activation of muscle cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are Primary tissue types?

A
  • muscle
  • Nervous
  • Connective
  • Epithelial
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

types of muscles

A

Cardiac
Smooth
Skeletal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Where do you find smooth muscles ?

A

Arteries
Gut
Bladder

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Skeletal Muscle is

Smooth or striated?

A

Striated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what is the name of the connective tissue surrounding Skeletal Muscles?

A

fascia or perimysium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the smallest compartment of skeletal muscle called ?

A

Fasciculus which contains a number of muscle fibers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which heals faster ?

Tendon or muscle

A

Muscles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Muscle fibers are in what orientation to each other ?

A

parallel

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Blood vessels location in a muscle

A

Blood vessels are wrapped in CT and are generally paralleled to fibers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Capillaries location in muscle

A

Run between fibers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which type of contraction can limit blood flow?

Dynamic or Isometric

A

Isometric

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the muscular NT

A

Acetylcholine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Muscle cell fibers contain

A

Nuclei
Mitochondria
Myoglobin
Myofibrills

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Muscle color is due to

A

Myoglobin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Myoglobin is a

A

Respiratory Pigment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Myofibrils are surrounded by

A

Sarcoplasmic Reticulum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Smallest contractile unit of a muscle fiber

A

Sarcomere

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Myofibril is a chain of

A

Sarcomeres laid end to end

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

The sarcomere has ——that keep contractile and regulatory proteins in the correct arrangement

A

Proteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Muscle fiber filled with

A

Sarcoplasm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Striated appearance is due to

A

Cross banding of myofibrils

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

A band is

A

Dark

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

I band is

A

Light

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Name proteins that are involved in force transmission to the enomysium

A
Actin
Alpha-actin
Vinculin
Talin
Dystrophin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Actomysin helps in

A

Muscle shortening

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Mechanism of muscle contraction

A

Nerve impulse excitation, which releases calcium ( from SR) into the sarcoplasm and causes contraction of the filament array

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Each thick filaments in the muscle fibers has ——myosin molecules

A

~200

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Mechanism of contraction

A

Sarcomeres shorten
H zone disappears
Distance reduced between successive z lines
Filaments maintain their length ( do not shorten)
Thin filaments slide past thick, thus increasing their overlap

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

How many sarcomeres per cm of muscle fiber

A

~4000

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Contraction speed depends on

A
  1. Rate of myosin heads attaching, rotating and detaching

2. Muscle length

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

Slow isoform

A

Type I

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

Fast Isoform

A

Type II

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

Isometric force is related to

A

Sarcomere length

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

Force is inversely related to

A

velocity of shortening

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

What is a power stroke?

A

When activated myosin heads now bind to the actin as the myosin head changes shape to bent, which causes the head to pull on the thin filaments

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

ADP and P are released from

A

Myosin heads

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

What is a motor unit?

A

group of muscle fibers that are functionally united

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

Small motor units are for

A

Finely controlled muscles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

Larger motor units are for

A

Coarse movement

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

Contraction force depends on

A
  1. # of motor units simultaneously activated

2. Cross sectional area of the muscles

42
Q

What is major difference in fiber types ?

A

speed of contraction

43
Q

Slow twitch

Speed of contraction

A

Type I 80-100 ms

44
Q

Fast Twitch

Speed of contraction

A

Type II

40 ms

45
Q

Types of fibers

A
Type I ( red , Fatigue resistant)
II a ( red,Fatigue resistant )
II X ( White , fatiguable)
46
Q

Does fiber type IIx have more contracting power or type I

A

Type IIx has 3X greater contracting power

47
Q

Type IIx has more or fewer mitochondria ?

A

Fewer

48
Q

Type IIx has more or less capillary supply?

A

Less or poorer

49
Q

Type IIx has —–stores of glycogen and phosphocreatine

A

Larger

50
Q

Type IIx fibers have

A

High activity of glycogenolytic and glycolytic enzymes

51
Q

Type IIx fibers in terms of contraction?

A

Powerful contractions for brief periods

52
Q

These kind of fibers have fast acting ATPases

A

II a and IIx

53
Q

These kinds of fibers have oxidative capacity

A

IIa and type I

54
Q

What type of neurons in type I fiber?

A

Small diameter
Slow conduction velocity
Low activation threshold

55
Q

What type of neurons in Type II fibers

A

Large diameter
Fast conducting velocity
Higher activation threshold

56
Q

Large motor units have what type of fibers

A

Fast

57
Q

Small motor units have what type of fiber

A

Slow

58
Q

Small/slow Motor units are used for

A

Posture/balance

59
Q

Fast motor units are used for

A

Jumping/lifting/throwing/sprinting

60
Q

In old age humans this type of fiber atrophy quicker

A

Type II

61
Q

How does training affect the proportions of fiber types

A

Doesn’t significantly affect it buy

Can affect the diameter specially type II

62
Q

3 types of muscle contractions

A
  • isometric
  • Eccentric
  • Concentric
63
Q

High force eccentric contraction is also called

A

Delayed onset muscle soreness

64
Q

Reasons for DOMS

A

Small # of fibers activated
Type II fibers may be selectively recruited ?
High load on few fibers–> ruptures of the fibers

65
Q

Skeletal muscle adaptability to strength training

A

Hypertrophic response

Muscle gets bigger

66
Q

Hypertrophic responses cause

A

Greater power

Greater anaerobic capacity

67
Q

Gradual hypertrophy occurs because of

A

Increased fiber diameter NOT increased fiber number

68
Q

Does proportion of different fiber types change in hypertrophy?

A

NOOOOO

69
Q

The —–content of tissues give them their shape

A

Protein

70
Q

Enzyme content determines

A

Function

71
Q

Amount of enzyme determines

A

Speed of enzyme process

72
Q

Side chains give proteins their

A

Special structure @ physiological pH

73
Q

Most abundant AA in muscles

A

Branched-chain AA

20%

74
Q

What is the most abundant free AA in muscle and plasma

A

Glutamine

75
Q

Protein structure classification

A

Primary
Secondary
Tertiary- 3D shape
Quaternery

76
Q

Major protein storage in body

A

No major storage other than skeletal muscle

77
Q

What happens to excess protein

A

Excess protein is oxidized and N excreted

78
Q

Strength training induce anabolism or catabolism

A

Anabolism

79
Q

Does endurance training induce anabolism

A

NO

80
Q

3 main purpose of protein breakdown

A
  • Degrades damaged proteins
  • Provides energy
  • AAs can be reused for synthesis of proteins and non proteins like glucose, ketones and fat
81
Q

Well trained athletes have —- post exercise turn over

Less or More?

A

Less

82
Q

Anabolic hormones

A
Growth hormone 
Insulin
Testosterone 
Triiodothyronine
Glucagon
83
Q

This hormone antagonizes actions of insulin

A

Growth hormone

84
Q

This hormone induces liver to release somatomedins

A

Growth hormone

85
Q

Growth hormone is most effective in stimulating

A

Collagen synthesis (CT)

86
Q

This hormone causes growth in bones of face, hands, feet & predisposition to diabetes

A

Growth hormone

87
Q

Growth hormone is not optimally effective for

A

Muscle growth

88
Q

Insulin stimulates —–synthesis

A

Protein

89
Q

Health risk of testosterone

A

Cardiovascular dz

Liver cancer

90
Q

Unit of enzyme activity measurement

A

International Unit: IU

91
Q

What is IU:

A

The amount of enzyme to convert one micromole of substrate to product in one minute under specified conditions

92
Q

SI unit for IU

A

Katal (Kat)

93
Q

What is 1kat

A

The amount of enzyme that will convert 1 mole of substrate to product in 1 sec ( in optimum conditions )

94
Q

Optimal temp for enzyme activity

A

25-37

95
Q

Warmer muscles have higher

A

Reaction rates thus better muscle performance

96
Q

What metal ions are essential for enzyme activation

A

Ca
Mg
Zn

97
Q

Allosteric Modulation

A

Reversible binding of small molecules to the enzyme at sites other than active sites-producing a conformation change in the structure of the enzyme molecule.

98
Q

Risks of taking more than needed protein >3g/day

A

Kidney damage

Increased serum lipoprotein levels (arteriosclerosis risk)

Dehydration

99
Q

95% of creatine in the body is in

A

Skeletal muscle

2/3 is phosphocreatine

100
Q

Liver and kidney can synthesize creatine from

A

Methionine
Arginine
Glycine

101
Q

Risks of consuming testosterone

A
Decrease in HDL
Acne
Inappropriate hair growth
Prostate enlargement 
Poor testicular function 
Liver damage
102
Q

Other performance enhancing drugs

A

Caffeine
Ephedrine
Pseudoephedrine
Beta agonist—stimulate effects of catecholamine hormones . Fight or flight