Chapter 18 ETC Flashcards

1
Q

four complexes of ETC

A

NADH-Q oxidoreducatase, succinate-Q reductase, Q-cytochrome c oxidoreductase, cytochrome c oxidase

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2
Q

three proton pumps of ETC

A

NADH-Q oxidoreducatase, Q-cytochrome c oxidoreductase, cytochrome c oxidase

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3
Q

complex 1

A

NADH-Q oxidoreducatase

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4
Q

complex 2

A

succinate-Q reductase

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5
Q

complex 3

A

Q-cytochrome c oxidoreductase

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6
Q

complex 4

A

cytochrome c oxidase

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7
Q

complex 1 function

A

transfer electrons from NADH to Q

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8
Q

complex 2 function

A

transfer electrons from FADH2 to Q

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9
Q

complex 3 function

A

transfer electrons from Q to cytochrome c

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10
Q

complex 4 function

A

transfer of electrons from cytochrome c to O2

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11
Q

electrons passed from ? to ? electrode potential

A

low to high

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12
Q

high/low electrode potential is indicative of high affinity for electrons

A

high

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13
Q

net reaction of complex 3

A

QH2 + 2cytC (ox) + 2H+ (matrix) goes to Q + 2cytC (red) + 4H+ (cytoplasm)

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14
Q

ETC pumps protons into ?

A

intermembrane space

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15
Q

complex 4 produces water in ?

A

matrix

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16
Q

superoxide dismutase reaction

A

2O2- + 2H+ goes to O2 + H2O2

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17
Q

catalase reaction

A

2H2O2 goes to O2 + 2H2O

18
Q

ATPsynthase structure

A

one gamma subunit, three alpha, three beta

19
Q

gamma subunit induces beta subunit into these three conformations

A

open, loose, tight

20
Q

open conformation of ATPsynthase

A

allows ATP to be released and allows ADP and Pi to enter

21
Q

loose conformation of ATPsynthase

A

holds ADP and Pi in place

22
Q

tight conformation of ATPsynthase

A

forces ATP synthesis from ADP and Pi

23
Q

number of protons transported across ATPsynthase per turn

A

12

24
Q

number of ATP made per turn

A

3

25
Q

number of proton transfers required to make one ATP

A

4

26
Q

ATP/O ratio for ATP synthesis

A

2.5 (10/4). 4 protons required for ATP synthesis. Ten protons pumped per NADH to reduce one oxygen.

27
Q

protons pumped per NADH

A

10

28
Q

G3P shuttle function

A

Allows NADH produced in glycolysis to be incorporated in ETC

29
Q

G3P shuttle net reaction

A

NADH + H+ +EFAD goes to NAD+ + EFADH2. EFADH2 transfers electrons to Q.

30
Q

malate-aspartate shuttle function

A

electrons transported from NADH to malate, malate moves into matrix from cytoplasm, malate gives electrons to NAD+. Glutamate is transported across membrane to cytoplasm by converting to aspartate.

31
Q

protons pumped per FADH2

A

6

32
Q

glycolysis yield

A

2 ATP, 2NADH

33
Q

pyruvate dehydrogenase yield

A

2 NADH

34
Q

CAC yield

A

2ATP, 6NADH, 2FADH2

35
Q

NADH and FADH2 yield from glycolysis and CAC for one glucose

A

10NADH and 2FADH2

36
Q

ATP yield from glycolysis and CAC for one glucose

A

4ATP

37
Q

10NADH pumps ? protons

A

100

38
Q

2FADH2 pumps ? protons

A

12

39
Q

112 protons pumped creates ? ATP

A

28

40
Q

net ATP yield of one glucose molecule through glycolysis, CAC and ETC

A

32