Chapter 12 Lipids Flashcards

1
Q

has polar and nonpolar region

A

amphipathic

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2
Q

palmitate structure

A

16C

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3
Q

oleate structure

A

18C cis w9

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4
Q

laurate structure

A

12C

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5
Q

Myristate structure

A

14C

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6
Q

Stearate structure

A

18C

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7
Q

Arachidate structure

A

20C

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8
Q

Behenate structure

A

22C

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9
Q

Lignocerate structure

A

24C

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10
Q

Palmitoleate structure

A

16C w9

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11
Q

linoleate structure

A

18C w9,12

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12
Q

linolenate structure

A

18C w9,12,15

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13
Q

arachidonate structure

A

20C w5,8,11,14

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14
Q

Longer fatty acids have (higher/lower) melting points

A

higher

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15
Q

more unsaturated fatty acids have (higher/lower) melting points

A

lower

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16
Q

three major types of membrane lipids

A

phospholipids, glycolipids, cholesterol

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17
Q

phosphoglyceride structure

A

glycerol with two fatty acids and one phosphate group which is in turn bound to alcohol group. All bound by peptide bonds.

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18
Q

Cause of respiratory distress syndrome

A

lack of lecithin (DPPC). Makes hard to breathe.

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19
Q

sphingosine

A

18-carbon amino alcohol with an unsaturated hydrocarbon chain. Can be used to make phospholipids.

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20
Q

more cholesterol makes membrane (less/more) fluid

A

less

21
Q

less cholesterol makes membrane (less/more) rigid

A

less rigid

22
Q

excess cholesterol precipitates and forms ?

A

gallstones

23
Q

cholesterol is the precursor of ? (3)

A

bile salts, steroid hormones, vit D

24
Q

bile salts help to break down ?

A

lipids

25
Q

cortisol functions to ?

A

increase the glucose glucose and glycogen concentration in the body

26
Q

increases the glucose glucose and glycogen concentration in the body

A

cortisol

27
Q

? have modified their lipids to accomodate their environment

A

archaebacteria

28
Q

modifications to lipids by archaebacteria

A

ether linkage (instead of peptide), branched chain, inverted stereochemisry

29
Q

arachaebacteria environment

A

high temp, high acid, high base

30
Q

lipid saturation (increases/decreases) melting point

A

increases

31
Q

amphipathic

A

polar and nonpolar region

32
Q

phospholipids and glycolipids form ?

A

bilayers

33
Q

ionized fatty acids form?

A

micelles

34
Q

driving force of assembly of bilayers

A

hydrophobic effect

35
Q

liposome structure

A

bilayer membrane

36
Q

membrane permeability is low for ? and ? molecules

A

charged (primary factor), large

37
Q

? are responsible for transport of molecules across the membrane

A

membrane proteins

38
Q

protein stucture that spans membranes

A

alpha helix (hydrophobic and nonpolar region)

39
Q

porin structure

A

beta barrel

40
Q

since porins lack ?, they do not show hydrophobic transmembrane regions

A

hydrophobic alpha helices

41
Q

lipid signalling molecules

A

prostaglandins

42
Q

prostaglandin synthesis starts with ?

A

release of a fatty acid from a membrane lipid followed by two oxidation steps

43
Q

prostaglandin synthesis is is catalyzed by ? located in the membrane

A

prostaglandin H2 synthase

44
Q

Aspirin acetylates ser530 to ?

A

inactivate prostaglandin H2 synthase

45
Q

membrane components have ? mobility

A

lateral

46
Q

virtually all naturally occurring fatty acids are (trans/cis)

A

cis

47
Q

Na+, K+ ATPase pumps out ? and pumps in ?

A

pumps out Na+ and pumps in K+

48
Q

transmembrane helices AAs have (positve/negative) delta G

A

positive

49
Q

? is on red blod cells to increase polariy to dissolve in hydrophilic environment

A

glycophorin